R signals at the neuromuscular junction and at synapses between neurons are carried by small molecules, called neurotransmitters, that are released from the presynaptic terminal and bind to ligand-gated ion channels in the postsynaptic membrane. When transmitter binds, a small pore opens through which ions flow, resulting in a transient depolarization or hyperpolarization of the membrane and tr...

Kiss of death D8 cytotoxic T cells are serial killers that slay one infected or cancerous cell after another. During each fatal encounter, an intercellular junction called the immunological synapse forms between killer and victim, according to researchers from Oxford University (Oxford, UK). Their work suggests new functions for the immunological synapse and supports the hypothesis that the imm...

This article briefly describes the legislative history of the old-age, survivors, and disability insurance (OASDI) and supplemental security income (SSI) provisions, as well as related Medicare and Medicaid provisions, of the Consolidated Omnibus Budget Reconciliation Act of 1985 (Public Law 99-272). It includes a chronology outlining the interaction of the budget reconciliation process with th...

The 2013 ‘Consolidated guidelines on the use of antiretroviral (ARV) drugs for treating and preventing HIV infection’ [1], released in July 2013, are the latest and most comprehensive of a series of important guidelines on antiretroviral therapy (ART) over the last decade from the World Health Organization (WHO). They were developed in response to important advances in the science and practice ...

Business Process Reengineering is a discipline in which extensive research has been carried out and numerous methodologies churned out. But what seems to be lacking is a structured approach. In this paper we provide a review of BPR and present ‘best of breed ‘ methodologies from contemporary literature and introduce a consolidated, systematic approach to the redesign of a business enterprise. T...

The use of a short consolidation treatment after autologous transplantation increases the complete response rate and relapse-free survival.

Fabrication and characterization of aluminum matrix composites containing different volume fractions of Ni3Al powder (5-40 Vol%) were investigated. Ni3Al powder was produced by mechanical alloying of elemental nickel and aluminum powder mixture. Al-Ni3Al composite parts were prepared using a powder metallurgy route involving two stages Al and Ni3Al powder mixtures were first compacted under 500...

Let T be a finite set of tiles, and B a set of regions Γ tileable by T. We introduce a tile counting group G(T,B) as a group of all linear relations for the number of times each tile τ ∈ T can occur in a tiling of a region Γ ∈ B. We compute the tile counting group for a large set of ribbon tiles, also known as rim hooks, in a context of representation theory of the symmetric group. The tile cou...