Most memory CD8 T cell subsets that have been hitherto defined are generated in response to infectious pathogens. In this study, we have characterized the CD8 T cells that survive priming conditions, devoid of pathogen-derived danger signals. In both a TCR-transgenic model and a model of contact hypersensitivity, we show that the priming of naive CD8 T cells under sterile inflammatory condition...

The aluminum alloy EN AW-7075 T6 is used in the automotive sector for its favourable strength-to-weight ratio. However, limited cold formability currently addressed by energy- and time consuming temperature assisted processes. In order to limit effort critical forming areas only, state of art shows promising results increasing blank range warm forming. design new processes an industrial context...

In this study, adhesive wear extension in axisymmetric fretting contacts is simulated by applying the Contact Oxygenation Concept (COC) which illustrates influence of loadings on oxygen transport within interface. Di-oxygen flow modeled using an Advection-Dispersion-Reaction (ADR) approach was formerly proposed assuming third body as a porous medium crossed atmospheric gases. It shown that ADR ...

The level set method is one of the most successful methods for the simulation of multi-phase flows. To keep the level set function close the signed distance function, the level set function is constantly reinitialized by solving a Hamilton-Jacobi type of equation during the simulation. When the fluid interface intersects with a solid wall, a moving contact line forms and the reinitialization of...

Kelly Cleland1,*, Haoping Zhu2, Norman Goldstuck3, Linan Cheng4, and James Trussell1,5 Office of Population Research, Princeton University, 218 Wallace Hall, Princeton, NJ 08544, USA Minhang Central Hospital, Shanghai Jiaotong University, Shanghai 201100, People’s Republic of China Reproduction Research South Africa, St John’s Rd, Sea Point, Cape Town 8005, South Africa Shanghai Institute of Pl...

We modify the formulation of Hertz contact theory between two elastic half-solids with axial symmetry and show that these modifications to Hertz's original framework allow the development of force laws of the form F [Please see symbol] z(n), 1 < n < ∞, where F is the force and z is the distance between the centers of the two solids. The study suggests that it may be possible to design physical ...

criticism of public extension services has resulted in various countries seeking alternative approaches for provision of these services. in all these approaches, extension personnel are the key factors to the success of the implementation. today, agricultural extension services in turkey bear the responsibility of the ministry of food, agriculture and livestock. a number of non-public extension...