Ahlgren, J. 2002. Studies on prediction of axillary lymph node status in invasive breast cancer. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1116. 63pp. Uppsala. ISBN 91-554-5221-3. Breast cancer is the most common malignancy among females in Sweden. Axillary lymph-node dissection is a standard procedure in the management of brea...

BACKGROUND The staging of axillary lymph nodes is critical to the management and prognosis of breast cancer, the most frequent cancer in females. Neoadjuvant therapy and lymph node dissection are recommended when malignant cells invade the lymph nodes. Therefore the pre-operative examination of these lymph nodes is crucial to treatment. METHODS In this study, we examined the effectiveness of ...

The axillary lymph node status is the most reliable prognostic indicator of recurrence and overall survival in patients with breast cancer. The current standard surgical procedure for the management of invasive breast cancer is the complete removal of the cancer with total axillary clearance. However, recently, selective sentinel lymph node mapping and biopsy is gaining acceptance as a useful a...

It is debated if all breast cancer (BC) patients with sentinel lymph node metastasis need axillary dissection (ALND). Based on clinical and biological factors, we explore a statistical model for predicting non (non-SNm) in positive SN (SN+).

Background: Due to the current trends towards replacing axillary dissection with radiotherapy, the need for more precise definition for different nodal stations becomes a must to ensure safe and adequate dose coverage. So, our study aimed to evaluate the coverage of axillary nodal volumes based on Project on Cancer of the Breast (PROCAB) guidelines, for cases previously treated with our standar...

The detection of regional lymph node metastases is important in cancer staging as it guides the prognosis of the patient and the strategy for treatment. Sentinel lymph node biopsy (SLNB) is an accurate, less invasive alternative to axillary lymph node dissection. The sentinel lymph node hypothesis states that the pathological status of the axilla can be accurately predicted by determining the s...

Male breast cancer (MBC) is considered as a rare disease that accounts for less than 1% of all breast cancers, and its treatment has been based on the evidence available from female breast cancer. Axillary sentinel lymph node biopsy (SLNB) is now regarded as the standard of care for both female and male patients without clinical and imaging evidence of axillary lymph node metastases, while inte...

Objective: To assess the accuracy of sentinel lymph node biopsy in breast cancer, therefore, reducing the morbidity of axillary clearance in patients having clinically impalpable axillary lymphnodes. Study Design: A Prospective study Place and Duration of Study: This study was conducted at the Department of Surgery, Unit II, Chandka Medical College / Hospital, Larkana from January 2014 to Decem...

We designed a 2-stage study to investigate chemotactic factor receptor 5 (CCR5) gene expression in breast cancer tissues and axillary lymph nodes and analyze the association between the CCR5-Î"32 gene polymorphism and the clinical features and prognosis of breast cancer patients. The first stage examined 72 cases of invasive ductal carcinoma and axillary lymph node tissue, 50 cases of breast fi...