background: endotracheal suctioning (ets) is one of the most common supportive measures in intensive care units (icu). ets may be associated with complications including hypoxia and tachycardia. closed system suctioning (css) decreases the rate of cardiorespiratory complication mainly due to continuation of ventilatory support and oxygenation during procedure. css has questionable efficacy, the...

introduction underdevelopment of the lung parenchyma associated with abnormal growth of pulmonary vasculature in neonates with congenital diaphragmatic hernia results in pulmonary hypertension which mandates smooth elective mechanical ventilation in postoperative period, for proper alveolar recruitment and oxygenation, allowing lungs to mature enough for its functional anatomy and physiology. d...

The objective of this study was to evaluate the effect of timing in the use of high-frequency oscillatory ventilation (HFOV) on the survival of children with severe acute hypoxemic respiratory failure and ARDS who were initially on conventional mechanical ventilation (CMV). Twenty-six consecutive patients, 17 males and 9 females, fell into two groups: the early intervention group (17 patients) ...

BACKGROUND The haemodynamic as well as the ventilatory consequences of mechanical ventilation can be harmful in critically ill neonates. Newly developed ventilatory lung protective strategies are not always available immediately and in an acute situation the haemodynamic changes caused by mechanical ventilation can affect the oxygen delivery considerably. We report the case of a male neonate wh...

The aim of this study was to compare high-frequency oscillatory ventilation (HFOV) with conventional mechanical ventilation (CMV) with and without surfactant in the treatment of surfactant-deficient rabbits. A previously described saline lung lavage model of lung injury in adult rabbits was used. The efficacy of each therapy was assessed by evaluating gas exchange, lung deflation stability and ...

The clinical efficacy of pulmonary surfactant (PS) combined with assisted ventilation was assessed for acute respiratory distress syndrome (RDS) management of term neonates. The total sample size was of 60 subjects. Group I: Experimental group, 30 cases were treated with standard of care with tracheal intubation, mechanical ventilation and PS (100-200 mg/kg). In case of hypoxaemia present even ...