Obtaining employment is often difficult for a person with epilepsy. Recent studies have shown that public attitudes towards epilepsy have improved'2 but finding ajob is still difficult for 25-75% of the 140 000 potential employees with epilepsy in the United Kingdom.34 It has been said that the reason for this difficulty is prejudice and discrimination which reflects a prevailing ignorance abou...

Experimental data indicate that nitric oxide (NO) may play a role in the pathophysiology of epilepsy. It is also possible that NO-mediated events are involved in the expression of the anticonvulsant action of some antiepileptics. The aim of this review was to assemble current literature data on the role of NO in the anticonvulsant action of antiepileptic drugs (AEDs). The influence of various N...

BACKGROUND/AIM In recent years ischemia-modified albumin (IMA) has been suggested as a marker that can be used in differentiating nonconvulsive conditions from epilepsy. The purpose of this study was to investigate changes in IMA levels caused by generalized clonic tonic (GTC) seizures. MATERIALS AND METHODS A total of 114 children presenting to the Karadeniz Technical Pediatric Emergency Pol...

Epilepsy affects 1-2 % of the population. For 30 % of these patients, their syndrome will be refractory to medical treatment. To improve our understanding and treatment of the epilepsies, we need to develop clinically relevant animal models. As temporal lobe epilepsy is often preceded by prolonged febrile seizures and in our population associated with a focal cortical dysplasia, we hypothesised...

Sir, Epilepsy is world wide health problem. Figures ranging from 1.28 to 8.87 per 1000 have been given in various studies from India.1 Very few neuroepidemiological studies have been possible in rural areas. This door-to-door survey was conducted in part of rural Rajasthan, with the aim to study the prevalence rate of active epilepsy and clinical profile including attitude and beliefs of people...

Epilepsy surgery in the left temporal lobe is associated with a high risk of naming decline. In the present study, in 45 patients with left temporal lobe epilepsy (TLE) and confirmed left hemisphere language dominance, 13 (29%) patients demonstrated postoperative decrement >or=5 naming failures in the Boston Naming Test (BNT). Multivariate discriminant analysis with age at onset of epilepsy, ag...

The death of any child is tragic. When the death is sudden and unexpected, it can seem especially incomprehensible. Henry was 4 years old when he died only a few weeks after his epilepsy diagnosis; his parents were devastated and never knew that death could occur; no physician had discussed the possibility with them. Henry was an otherwise healthy child, had a history of febrile seizures, and d...

INTRODUCTION Febrile seizure (FS) is the most common paediatric neurological problem. The purpose of this study was to determine the frequency of afebrile seizures subsequent to FS in children with initial FS and to evaluate its risk factors. METHODS A prospective study was conducted on all children (age 6 months to 6 years) referred with initial FS to the Shahid Sadoughi Hospital, Yazd, Iran...

Febrile seizures are common and mostly benign. They are the most common cause of seizures in children less than five years of age. There are two categories of febrile seizures, simple and complex. Both the International League against Epilepsy and the National Institute of Health has published definitions on the classification of febrile seizures. Simple febrile seizures are mostly benign, but ...

PURPOSE To investigate the prevalence of epilepsy in schoolchildren aged 7-17 in the province of Kayseri together with the accompanying risk factors. METHODS Ten thousand individuals selected using the "stratified cluster sampling method" from a total population of 259,428 students within the borders of Kayseri city center constituted the study sample. A questionnaire was prepared in line wit...