In previous investigations an impact of cellular copper homeostasis on ageing of the ascomycete Podospora anserina has been demonstrated. Here we provide new data indicating that mitochondria play a major role in this process. Determination of copper in the cytosolic fraction using total reflection X-ray fluorescence spectroscopy analysis and eGfp reporter gene studies indicate an age-related i...

Transdermal patches were developed for a low oral bioavailable drug, lacidipine (LCDP) employing ethyl cellulose/Eudragit RL100 and polyvinyl pyrollidone (PVP) as polymeric matrices. The effect of binary mixtures of polymers on physicochemical properties such as thickness, moisture absorption and moisture content; in vitro release, ex vivo permeation and mechanical properties was evaluated. Ex ...

The nonlinear bending behavior of sector graphene sheets is studied subjected to uniform transverse loads resting on a Winkler-Pasternak elastic foundation using the nonlocal elasticity theory. Considering the nonlocal differential constitutive relations of Eringen theory based on first order shear deformation theory and using the von-Karman strain field, the equilibrium partial differential eq...

A polyvinylpyrrolidone (PVP)/Ag nanocomposite was prepared by reduction of silver nitrate in ethylene-glycol in the presence of a polymeric protective agent (i.e., poly (N-vinylpyrrolidone)). The size dependent color variation of this nanocolloid is a clear indication of the presence of Ag as nanoparticles in the polymer matrix. The nonlinear optical properties were studied by Z-scan technique ...

The dinuclear copper complex (alpha-cyano-4-hydroxycinnamic acid (CHCA) copper salt (CHCA)(4)Cu(2)), synthesized by reacting CHCA with copper oxide (CuO), yields increased abundances of [M + xCu - (x-1)H](+) (x = 1-6) ions when used as a matrix for matrix-assisted laser desorption ionization (355 nm Nd:YAG laser). The yield of [M + xCu - (x-1)H](+) (x = 1 to approximately 6) ion is much greater...

Novel ternary nanocomposite films based on polyvinylpyrrolidone copper nanoparticles graphene oxide (PVP/Cu/GO) were prepared using electrochemical deposition technique Fluorine doped tin (FTO) substrate. This facile and effective approach has been proven to be very useful for the fabrication of inexpensive, high-performance devices. To achieve uniform films, three components nanocomposites mix...

Postural control changes were studied in 27 patients with Parkinson's disease after unilateral posteroventral pallidotomy (PVP). Patients were evaluated before PVP and at 3, 6 and 12 months post-PVP, both 'off' and 'on' parkinsonian medications, with selected evaluation tools representing functional performance, functional balance and posturographic components of balance. The majority of variab...

OBJECTIVES To investigate whether the presence of detrusor overactivity (DO) influences storage symptoms after photoselective laser vaporization of the prostate (PVP) for benign prostatic hyperplasia (BPH). METHODS A total of 149 patients who underwent PVP were included in this retrospective study. All patients underwent a preoperative evaluation including multichannel video urodynamics. The ...

OBJECTIVES The objective of this review is to provide an evidence-based update on laser surgery for BPH with a focus on comparing Greenlight Photoselective Vaporisation of the Prostate (PVP) to Holmium Laser Enucleation of the Prostate (HoLEP). METHODS We reviewed all HoLEP and PVP papers identified by a Pubmed search using the keywords: laser, prostate, BPH, holmium, HoLE, PVP and greenlight...

BACKGROUND AND PURPOSE The patient populations that are most likely to benefit from percutaneous vertebroplasty (PVP) are uncertain. Our purpose was to evaluate the effect of the age of vertebral compression fracture (VCF) on clinical improvement after PVP. METHODS We performed a retrospective review of charts of patients who had undergone PVP for painful osteoporotic VCFs at our institution....