BACKGROUND Umbilical cord blood expresses cluster of differentiation (CD) 26, a fraction of CD34 + cells, negatively regulating in vivo homing and engraftment of hematopoietic stem cells. CD26 is highly expressed in various cells such as HSCs, immune cells, fibroblasts, and epithelial cells. It has been shown that inhibition of the CD26 on CD34 + cells improve the efficiency of transplantation ...

Many investigators have used xenogeneic, especially murine stromal cells and fetal calf serum to maintain and expand human stem cells. The proliferation and expansion of human hematopoietic stem cells in ex vivo culture were examined with the goal of generating a suitable protocol for expanding hematopoietic stem cells for patient transplantation. Using primary fetal liver cells, we established...

Background: Hemoglobin (Hb) and hematocrit (Hct) have been used routinely in the diagnosis of neonatal anemia and polycythemia. Objective: To measure the cord blood Hb and Hct and to determine their association with maternal Hb and Hct. Methods: 170 healthy neonates born through normal vaginal delivery with gestation age of 37-42 wks and birth weight of 2.5-4 kg, and their mothers were included...

background: studies have demonstrated the effect of different dietary fats on blood pressure (bp) in general population. however, these associations have not yet been described in people with spinal cord injury (sci). methods: referred patients to brain and sci research center between 2011 and 2014 have been invited to participate. only paraplegic individuals were recruited and patients with in...

background: chronic graft versus host disease (cgvhd) is one of the most serious potential complications of allogeneic bone marrow transplantation. study design and method: we analyzed the incidence of cgvhd and its associated risk factors in a group of 161 iranian recipients of hla-identical sibling transplants, with at least 90 days post-transplantation survival. in the majority of cases (n=7...

The current supply of red blood cells expressing rare blood groups is not sufficient to cover all the existing transfusion needs for chronically transfused patients, such as sickle cell disease homozygous carriers, because of alloimmunization. In vitro production of cultured red blood cells is slowly emerging as a possible complement to the existing collection-based red blood cell procurement s...

We previously reported that CD31(bright) cells, which were sorted from cultured AC133(+) cells of adult peripheral blood cells, differentiated more efficiently into endothelial cells than CD31(+) cells or CD31(-) cells, suggesting that CD31(bright) cells may be endothelial precursor cells. In this study, we found that CD31(bright) cells have a strong ability to release cytokines. The mixture of...