MANY of the stationary corneal opacities causing diminution of vision are central, avascular, and superficial, and are surrounded by clear cornea or have a neighbouring peripheral clear corneal area of 4 x 4-5 mm. Donor homogenous corneal grafts are not always available, but a rectangular lamellar autogenous corneal. graft can be dissected and turned 1800 so that the clear lamellae are brought ...

PURPOSE To elucidate the temporal sequence of events leading to new capillary sprouting in inflammatory corneal angiogenesis. METHODS Angiogenesis was induced by corneal suture placement in Wistar rats. The inflamed region was examined by time-lapse in vivo confocal microscopy for up to 7 days. At 6 and 12 hours and 1, 2, 4, and 7 days, corneas were excised for flat mount immunofluorescence w...

PURPOSE To evaluate the difference in the effect of 2 speeds of intraocular lens (IOL) insertion on the clear corneal wound structure. SETTING Ouchi Eye Clinic, Kyoto, Japan. DESIGN Prospective randomized clinical trial. METHOD Eyes that had phacoemulsification and Acrysof IQ IOL implantation using a screw-plunger type injector were randomly divided into 2 equally sized groups as follows:...

BACKGROUND To evaluate the distribution of biometric parameters and corneal astigmatism using the IOLMaster device before phacoemulsification in cataract patients in Central China. METHODS Consecutive cataract patients were recruited at the Central Hospital of Wuhan between January 2015 and June 2016. Ocular axial length (AL), keratometry values, anterior chamber depth (ACD) and horizontal co...

Macromolecules from normal rabbit cornea and cornea containing a 2-mm diameter button of scar tissue were biosynthetically labeled with 35S-sulfate and 3H-glucosamine in vivo and in organ culture. Labeled macromolecules, including proteoglycans (PGs) extracted from the normal cornea, scar tissue, and corneal tissue adjacent to the scar with guanidine hydrochloride were chromatographed on DEAE-S...

A knowledge of the shape of the cornea is of major importance for the planning and monitoring of surgery, and for the correct diagnosis of corneal diseases. Many authors have studied the geometry of the second corneal surface in the central region and it has been stated that there is a high correlation between the central radii of curvature and asphericities of the two corneal surfaces. In this...

PURPOSE To evaluate a novel 3D culture model of the corneal stroma and apply it to investigate how key wound-healing growth factors regulate the mechanics of corneal keratocyte migration. METHODS Rabbit corneal keratocytes were seeded within collagen matrices that were compacted using external compression. Six-millimeter-diameter buttons were then incubated in media supplemented with 10% FBS,...

OBJECTIVE To report the outcome of mushroom keratoplasty for the treatment of full thickness corneal disease in pediatric patients with healthy endothelium. METHODS A retrospective analysis of pediatric patients who underwent mushroom keratoplasty. The medical records of pediatric patients suffering from full thickness corneal stromal disease with normal endothelium who underwent mushroom ker...

BACKGROUND A new procedure to correct myopia that does not disturb the cornea in the optical zone and avoids injuring the corneal epithelium could be a key advance in corneal refractive surgery. The aim of this study is to observe the refractive change in the adult rabbits undergoing femtosecond laser-assisted multilayer intrastromal ablation in the mid-periphery of the cornea without injury of...

PURPOSE To evaluate the performance of a new system for obtaining corneal lamellar grafts of preset sizes. The system consists of the combination of an artificial anterior chamber (MALKS) and an automated microkeratotome (MASYK). METHODS A prospective study was performed. Lamellar tissue was obtained with the microkeratotome from 40 human corneoscleral buttons mounted in the artificial anteri...