نتایج جستجو برای: coronary ligation

تعداد نتایج: 215025  

Journal: :Circulation research 1990
T M Argentieri L H Frame T J Colatsky

The passive electrical properties of subendocardial Purkinje fibers surviving in infarcted regions of canine ventricle 24 hours after coronary ligation were studied by using microelectrode techniques and cable theory. In normal hearts, cells within the subendocardial Purkinje fiber strands were found to be well coupled to each other but electrically isolated from neighboring myocardium. Voltage...

Journal: :The Cardiothoracic Surgeon 2022

Abstract Background Giant coronary artery aneurysms (GCAA) are a rare disease entity with an estimated incidence of 0.02%. Atherosclerosis is the most common underlying factor in adulthood. Management guidelines lack support large-scale studies. Case presentation We present case 58-year-old Caucasian male complaints stable dyspnea who was found to have GCAA right (RCA). Further evaluation revea...

2017
Xuelian Wang Qingqing Xu Tianqi Li Yaocong Rong Weilin Hong Yan Huang Xingui Guo

Pulmonary hypertension due to left heart disease is associated with poor outcomes. This study investigated the beneficial effects of isosorbide dinitrate (ISDN) inhalation on pulmonary pressure and ventricular remodeling in a rat model of heart failure (HF) following myocardial infarction (MI). To assess the effect of ISDN on pulmonary pressure, 20 male Sprague-Dawley (SD) rats were randomized ...

Journal: :The heart surgery forum 2006
Geng-Hua Yi Kun-Lun He Nicholas C Dang Myung Jae Lee Patrick Cahalan Aftab R Kherani An Gu Daniel Burkhoff Jie Wang

BACKGROUND As the number of patients with diffuse coronary artery disease continues to grow, there is renewed interest in alternative methods of perfusing the ischemic myocardium. We tested the feasibility of myocardial retroperfusion via a direct left ventricle-to-great cardiac vein (LV-GCV) conduit to support regional contractility in this setting. METHODS LV-GCV flow was established using ...

2017
Philipp Stieger Jan‐Marcus Daniel Christiane Thölen Jochen Dutzmann Kai Knöpp Dursun Gündüz Muhammad Aslam Marian Kampschulte Alexander Langheinrich Silvia Fischer Hector Cabrera‐Fuentes Yong Wang Kai C. Wollert Johann Bauersachs Rüdiger Braun‐Dullaeus Klaus T. Preissner Daniel G. Sedding

BACKGROUND Following myocardial infarction (MI), peri-infarct myocardial edema formation further impairs cardiac function. Extracellular RNA (eRNA) released from injured cells strongly increases vascular permeability. This study aimed to assess the role of eRNA in MI-induced cardiac edema formation, infarct size, cardiac function, and survival after acute MI and to evaluate the therapeutic pote...

2015
Li Zhang Zhuo-Kun Gan Li-Na Han Hao Wang Jie Bai Guo-Juan Tan Xiao-Xia Li Ya-Ping Xu Yu Zhou Mei-Liang Gong Mo-Si Lin Xiao-Yang Han

BACKGROUND Myocardial infarction (MI) has likely contributed to the increased prevalence of heart failure (HF). As a result of reduced cardiac function, splanchnic blood flow decreases, causing ischemia in villi and damage to the intestinal barrier. The induction of heme oxygenase-1 (HO-1) could prevent, or lessen the effects of stress and inflammation. Thus, the effect and mechanism thereof of...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Chanil Moon Melissa Krawczyk Dongchoon Ahn Ismayil Ahmet Doojin Paik Edward G Lakatta Mark I Talan

Erythropoietin (EPO), well known for its role in stimulation of erythropoiesis, has recently been shown to have a dramatic neuroprotective effect in animal models of cerebral ischemia, mechanical trauma of the nervous system, and excitotoxins, mainly by reducing apoptosis. We studied the effect of single systemic administration of recombinant human EPO (rhEPO) on left ventricular (LV) size and ...

شرما, د, شکهار, ای, پاندی, پ,

Coronary artery reperfusion which has become one of the important therapeutic interventions is associated with development of cardiac arrhythmias. The present investigation was carried out to study the role of beta receptor blocking agents with different properties on reperfusion induced ventricular arrhythmias in intact rabbit heart. After anaesthesia the rabbit hearts were subjected to 30 min...

Journal: :Circulation 1978
T Peter M K Heng B N Singh P Ambler H Nisbet R Elliot R M Norris

Myocardial creatine phosphokinase (CPK) activity and myocardial blood flow (MFB, 15 +/- mu microspheres) were measured at 24 hours after ligation of the left anterior descending coronary artery in nine untreated anesthetized dogs, in eight dogs pretreated with intravenous propranolol 5 mg/kg and in eight which had both pretreatment as well as infusion of propranolol (1.25 mg/kg/hour) after occl...

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