OBJECTIVE To compare the effect of two different corticosteroid types in bilateral and symmetrical knee osteoarthritis (OA). METHODS One hundred and twenty-six patients received injections of methylprednisolone acetate (MP) in one knee and triamcinolone hexacetonide (TH) in the contralateral knee. Patients were evaluated before injection and 2, 4, 8, 12, and 24 weeks after. RESULTS Mean pat...

BACKGROUND If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS(R) gives an eightfold concentrate platelets of patients own blood. Injection of these platelets in the attachment of the fascia to the os calcis might...

OBJECTIVE To compare the clinical effectiveness of local corticosteroid injection, standard non-steroidal anti-inflammatory drugs, and simple analgesics for the early treatment of lateral epicondylitis in primary care. DESIGN Multicentre pragmatic randomised controlled trial. SETTING 23 general practices in North Staffordshire and South Cheshire. PARTICIPANTS 164 patients aged 18-70 years...

BACKGROUND Corticosteroid injection has a wide range of success in adhesive capsulitis but the reason for this has not yet been explained. We hypothesized that this difference might be due to the distribution of the corticosteroids injected into the joint cavity because particulate steroid deposits in the capsule and will not be moved over time by shoulder motion. OBJECTIVES The purpose of th...

OBJECTIVE To assess the effects of one intra-articular corticosteroid injection two weeks prior to an exercise-based intervention program for reducing pain sensitivity in patients with knee osteoarthritis (OA). DESIGN Randomized, masked, parallel, placebo-controlled trial involving 100 participants with clinical and radiographic knee OA that were randomized to one intra-articular injection on...

OBJECTIVE This study was performed to determine the effect of antenatal corticosteroid the interval between administration and delivery affect on neonatal outcomes. MATERIAL AND METHODS An observational study was performed on all deliveries between 28-34 weeks gestation where delivery occurred vaginally after completing a single course of antenatal corticosteroid (dexamethasone). Women were d...

Background: Plantar fasciitis was initially thought to be an acute inflammatory disease, but histology findings show that it is a chronic degenerative process leading pain at the calcaneal insertion without any inflammation. The diagnosis of plantar mainly based on clinical symptoms, like heel and tightness, diagnostic imaging not routinely required. Injection autologous blood can help stimulat...

BACKGROUND The outcomes of corticosteroid injection for trigger finger are well documented only with short-term follow-up. The purpose of this investigation was to determine the long-term effectiveness of a single injection and to examine predictors of success up to ten years after injection. METHODS This case series analyzed 366 first-time corticosteroid injections in flexor tendon sheaths f...

Melkersson-Rosenthal syndrome is an uncommon disorder which is presented by a triad of lip swelling, facial nerve palsy, and a fissured tongue. A number of treatments have been reported for this syndrome with variable outcomes. We have reported a 38-year-old female patient with lower lip swelling and a fissured tongue on clinical examination. She was also suffering from facial nerve paralysis s...

OBJECTIVE Describe the management of subglottic stenosis in a patient with Wegener's granulomatosis. MATERIAL AND METHOD Case report. RESULTS We report the case of a 26-year-old woman who presented Wegener granulomatosis and subglottic stenosis, with renal, skin, oropharyngeal, nasal, and paranasal locations. Medical treatment had cured all the locations except the subglottic stenosis. An e...