نتایج جستجو برای: costimulatory molecule

تعداد نتایج: 136835  

Journal: :The Journal of Experimental Medicine 1991
G A van Seventer W Newman Y Shimizu T B Nutman Y Tanaka K J Horgan T V Gopal E Ennis D O'Sullivan H Grey

Many ligands of adhesion molecules mediate costimulation of T cell activation. The generality of this emerging concept is best determined by using model systems which exploit physiologically relevant ligands. We developed such an "antigen-specific" model system for stimulation of resting CD4+ human T cells using the following purified ligands: (a) major histocompatibility complex class II plus ...

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