a lot of researches have investigated the effects of topical cyclosporine a on the eye surface layers' diseases. by now the main limitation in cyclosporine application is the low permeation of the drug into the posterior segments of the eye. the aim of present study was to formulate high permeable dosage form can be beneficial in the topical treatment of the uveitis. to reach higher corneal dru...

The purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. A 32 full factorial design was employed to study the effect of independent variables like Carbopol-934P and hydroxypropyl methylcellulose K100M, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...

development of resistant strains of pathogens to many fungicides as well as fungicide residues in food stuff have been resulted in attemps to develop biological agents as alternative methods to control post-harvest diseases. practical use of microorganisms requires formulated products that meet a number of criteria. in this study different carriers for powder formulation of p.guilliermondi were...

background: anti-microbial agents have been used as a chemotherapeutic agent to improve oral health. this in vitro study was carried out to determine antimicrobial efficacy of different toothpastes and mouthrinses against the oral pathogens.     methods: a total of five toothpastes and five mouthrinses were tested for their antimicrobial activity against three oral pathogens namely, streptococc...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

     Thimerosal, which is approximately 50% mercury by weight is a preservative widely used in vaccines since the 1930’s. It meets the requirements for a preservative as set forth by Pharmacopeia challenge test and has been shown to be effective against a broad spectrum of pathogens. In July 1999, the Public Health Service agencies and vaccine manufacturers agreed that thimerosal should be redu...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

In this work, we review the main existing theories for electromagnetic stress–energy tensor in dielectric media — a problem directly related to century-long debate regarding correct momentum of light media, known as Abraham–Minkowski controversy. The theoretical validity formulations is analyzed terms symmetry and invariance requirements tensors. We also present position- time-dependent numeric...