RESEARCH DESIGN AND METHODSdFracture-related hospitalization was defined using International Classification of Diseases, 9th revision, codes (733.1–733.19, 733.93– 733.98, or 800–829). We calculated the incidence rate of fracture-related hospitalization by age and used Cox proportional hazards models to investigate the association of diabetes with risk of fracture after adjustment for demograph...

Methods: To address this we retrospectively followed 7620 patients who underwent CABG between April 2001 and March 2006. Logistic regression was used to risk adjust in-hospital outcomes. Cox proportional hazards analysis was used to risk adjust Kaplan-Meier freedom from death curves. Outcomes were adjusted for American Heart Association and American College of College of Cardiology recommended ...

BACKGROUND Multivariable models are frequently used in the medical literature, but many clinicians have limited training in these analytic methods. Our objective was to assess the prevalence of multivariable methods in medical literature, quantify reporting of methodological criteria applicable to most methods, and determine if assumptions specific to logistic regression or proportional hazards...

We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of ℓ1 and ℓ2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a regularization path. We demonstrate the efficacy of our algorithm on real and simulated data sets, and find considerable speedup between our algori...

Methods We retrospectively evaluated 140 consecutive patients with NICM who underwent delayed hyperenhancement cardiac MRI between 2002 and 2009. A Cox proportional hazards model was used to evaluate the association between RVEF and the composite outcome of death, left ventricular assist device implantation, or heart transplantation. Predictors of RVEF were evaluated using a multivariable linea...

Cognitive impairment is associated with increased mortality, depending on the severity of impairment. We analyzed data from the Cardiovascular Health Study (CHS), using Cox proportional hazards regression models to quantify the effect of the impairment. After adjustment for age, sex, and medical risk factors, we found the resulting relative risks to range from 1.19 for mild impairment to 1.98 f...

We develop an analog of the likelihood ratio test for Cox proportional hazards models fitted to sample survey data. We look at methods for computing the asymptotic distribution and at ways of improving the small-sample performance. The methods are illustrated with examples using data from the National Health and Nutrition Examination Survey and from a stratified case-cohort study.

This study involved conducting a survival analysis by fitting Cox proportional hazards model to Korea Labor Panel data analyze the impact of parental job loss on children’s delayed admission colleges and universities in South Korea, using 376 subjects whose education levels were college-level or higher. Since are interval- right-censored, we compared three imputation methods: simple omission, a...

How old are young people when they start having sex? Although this question is important for educators and policymakers, its answer can easily mislead due to methodology that does not take into account age-censoring generational trends. This study investigated whether 1-year birth-year cohorts be jointly modeled by Cox proportional hazards regression estimate sexual debut ages investigate age t...