Three 1-methoxy analogs of CP-47,497 (7, 8, and 19) have been synthesized and their affinities for the cannabinoid CB(1) and CB(2) receptors have been determined. Although these compounds exhibit selectivity for the CB(2) receptor none have significant affinity for either receptor. Modeling and receptor docking studies were carried out, which provide a rationalization for the weak affinities of...

Abstract We show that there exist symplectic structures on a $$\mathbb {CP}^1$$ CP 1 -bundle over {CP}^2$$ 2 do not admit compatible Kähler structure. These were originally constructed by Tolman and they have Hamiltonian $${\mathb...

Transducing bacteriophages CP-51 and CP-53 were compared. Unlike CP-51, CP-53 appeared to be a lysogenizing phage. CP-51 gave greater frequencies of co-transduction for linked markers than did CP-53. CP-51 was found to be a larger phage which carried more deoxyribonucleic acid (DNA) than CP-53. CP-51 DNA contained about 43% guanine plus cytosine and in addition contained 5-hydroxymethyluracil i...

The most general Two Higgs Doublet Model (2HDM) allows both for the explicit and the spontaneous CP violation in the scalar sector. Here we discuss CP violation in terms of basisindependent quantities and show how using two different sets of known CP-odd weak-basis invariants one can distinguish between CP conservation, explicit CP violation and spontaneous CP violation. The special case of CP ...

Two unusual compounds, [{Cp*Rh(ZnCp*)(2)(ZnMe)(ZnCl)}(2)] (1) and [Cp*(2)Rh][(Cp*Rh)(6)Zn(18)Cl(12)(mu(6)-Cl)] (2), both bearing closed shell 18-electron square pyramidal Cp*RhZn(4) building units were obtained by combined Ga/Zn, Me/Cp* and Me/Cl exchange upon treatment of [Cp*Rh(GaCp*)(2)(GaCl(2)Cp*)] with ZnMe(2) (Cp* = pentamethylcyclopentadienyl).

Spectroelectrochemical studies of the intervalence charge transfer (IVCT) characteristics of both diastereoisomeric forms of the dinuclear complex [{Ru(bpy)2}2(mu-dpi-)]n+ [bpy=2,2'-bipyridine; dpi-=4,5-di(2-pyridyl)imidazolate] showed that the degree of inter-metal electronic coupling (or valence delocalization) is dependent on stereochemical identity. Increasing the relative concentration of ...