OBJECTIVE This study examined whether racial identity moderates the relation between pain and quality of life (QOL) in children with sickle cell disease (SCD). METHODS 100 children 8-18 years of age with SCD participated during a regularly scheduled medical visit. Children completed questionnaires assessing pain, QOL, and regard racial identity, which evaluates racial judgments. RESULTS Ana...

INTRODUCTION Characterization of the quality of life (QOL) in Alzheimer's disease (AD) scale within the context of a clinical trial may inform its applicability in future trials. METHODS Using data from 1322 patients enrolled in two phase-III studies (EXPEDITION 1 [NCT00905372] and 2 [NCT00904683]) of intravenous solanezumab in outpatients with mild AD dementia, correlations between patient- ...

PURPOSE OF REVIEW The purpose of this study was to review the current evidence for quality of life (QOL) in patients with kidney stone disease (KSD). RECENT FINDINGS A review of literature from inception to May 2016 for all prospective English language articles on QOL in patients with KSD was done. QOL studies post urological procedures or ureteric stents were excluded. Nine studies (1570 pat...

Abstract Background Awareness of factors associated with quality of life (QOL) in patients with beta-Thalassemia major (&beta-TM) is necessary to develop clinical programs in order to improve social support and QOL in &beta-TM patients. This study aimed to examine QoL, depression, anxiety, and stress in &beta-TM patients in Ahvaz, Iran. Materials and Method A cross-sectional study w...

Mounting evidence for response shifts in quality of life (QOL) appraisal indicates the need to include direct measurement of the appraisal process itself as a necessary part of QOL assessment. We propose that directly assessing QOL appraisal processes will not only improve our ability to interpret QOL scores in the traditional sense, but will also yield a deeper understanding of the appraisal p...

BACKGROUND Quality of life (QoL) is an important outcome for people with dementia living in care homes but usually needs to be rated by a proxy. We do not know if relative or paid carer proxy reports differ. We conducted the first systematic review and meta-analysis of data investigating whether and how these proxy reports of QoL differ. METHODS We searched four databases: Medline, Embase, Ps...

BACKGROUND Facial port-wine stains (PWS) are considered by some an aesthetic skin problem, yet impact on quality of life (QoL) has not been objectively documented. OBJECTIVE We sought to (1) characterize the effect of PWS on QoL in adults, (2) to identify the clinical and demographic factors that affect QoL, and (3) to compare our results with QoL studies in other skin conditions. METHODS I...

OBJECTIVES Infertility has a significant impact on a women's quality of life (QOL). Infertile women face with physical and mental challenges during their postmenopausal period. Therefore, the present study aimed to evaluate the QOL among Iranian infertile women in the postmenopausal period using a valid and reliable instrument. METHODS In this cross-sectional study both snowball and social ne...

PURPOSE Colorectal cancer (CRC) survivors are currently living longer due to better therapies but they also need to maintain their quality of life (QoL). QoL is increasingly being used as primary outcome measure in clinical studies. This study was designed to gain knowledge about QoL during chemotherapy across different lines and different regimens. METHODS The study comprised 101 CRC out pat...