Vascular acrosyndromes constitute a common reason for physician visits. They are associated with connective tissue disease; for example, 90% of patients with scleroderma experience Raynaud's phenomenon. The rheumatologist must strive to establish the diagnosis, to identify a potential underlying cause, and to prescribe effective treatment when the symptoms are incapacitating. Raynaud's phenomen...

Raynauds phenomena (RP) is a commonly encountered clinical manifestation which may be primary or secondary to underlying disease. There is imbalance between vasoconstricting and vasodilating factors. Physical examination, nailfold capillaroscopy and immunological tests can differentiate primary from secondary RP. Treatment involves prevention of RP so that permanent ischemic damage i.e. gangren...

The excitation mechanism of low degree acoustic modes is investigated through the analysis of the stochastic time variations of their energy. The correlation between the energies of two different modes is interpreted as the signature of the occurrence rate of their excitation source. The different correlations determined by Foglizzo et al. (1998) constrain the physical properties of an hypothet...

The study of the hard (E ∼ > 10 keV) energy spectra of X–ray binary pulsars can give a wealth of information on the physical processes that occur close to the neutron star surface. Extreme matter regimes are probed, and precious information on how matter and radiation behave and interact in critical conditions can be obtained. We will give an overview on the most recent results obtained by RXTE...

Over a decade of research has investigated the verbal overshadowing effect. This phenomenon, first demonstrated by Schooler and Engstler-Schooler (1990), indicates that verbally describing a nonverbal stimulus (such as a face) can impair subsequent attempts at identification of the stimulus. Taken together, the current special issue on verbal overshadowing explores three critical aspects of the...

1. Evidence has been found that Northrop's phenomenon (so called by us) is produced in the digestion of casein or hemoglobin brought about by trypsin, papain, and pepsin either crude or crystalline in the presence of gelatin. 2. Anson's and Kunitz' methods permit the measure of proteolytic activity of any protease on casein or hemoglobin substrate in the presence of gelatin, even in very small ...

Figure 1. Ischemic ulceration and necrosis of left middle finger. DESCRIPTION A 35-year-old man presented with a 3-year history of episodic fingertip pain with associated discoloration triggered by cold exposure. His job required activities in a subzero walk-in freezer, which exacerbated pain and discoloration. The middle fingertip wound began spontaneously 3 months prior and worsened despite m...

FROM January 1920 to December 1945, inclusive, Raynaud's disease, Raynaud's phenomenon, or questionable Raynaud's disease was diagnosed in 756 female patients at the Mayo Clinic. Data gleaned from a critical review of the clinical records and from follow-up questionnaires constitute the basis for the present report. In 1945 Hines and Christensen,' in a similar study of Raynaud's disease among m...