This study was designed to examine the pathogenesis of the excretory defect produced by bilateral ureteral obstruction in the rat. After release of obstruction of 24 hr duration glomerular filtration rate was reduced to 20% of normal. Free flow proximal tubular pressure was normal, excluding residual obstruction as a cause of depressed filtration, and indicating that an intrarenal hemodynamic a...

The objective of this research was to evaluate the potential for separating α-lactalbumin from pasteurized milk by using tangential flow membrane filtration. Filtration was carried out with a Purosep 7000 series membrane filtration unit (SmartFlow Technologies) with a regenerated cellulose membrane at 26°C and a transmembrane pressure of 186 kPa. The protein in the permeate was >80% α-lactalbum...

For microalgae biorefinery, membrane process is a suitable technology for biomolecules (i.e., proteins, lipids or carbohydrates) fractionation due to the simplicity in operation, flexibility implementation and potential processing large volumes. Here objective was microfiltrate aqueous extracts, after cell disruption clarification, concentrate retentate recover hydrophilic proteins permeate. Ho...

A dead-end filtration model that includes the three main fouling mechanisms mentioned in Hermia (i.e., cake build-up, complete pore blocking, and pore constriction) and that was based on a constant trans-membrane pressure (TMP) operation was extensively modified so it could be used for a sidestream configuration membrane bioreactor (MBR) situation. Modifications and add-ons to this basic model ...

A photosensitizer, meso-tetra(4-hydroxyphenyl)porphyrin, was incorporated into sub-150 nm nanoparticles using the emulsification-diffusion technique in order to perform sterilization by filtration using 0.22 microm membranes. The three selected polyesters (poly(D,L-lactide-co-glycolide), (50:50 PLGA, 75:25 PLGA) and poly(D,L-lactide (PLA)) for the nanoparticle production were all amorphous in n...

Microalbuminuria, an early feature of diabetic nephropathy, indicates intrarenal endothelial damage. In type 2 diabetes, microalbuminuria is strongly related to insulin resistance. We therefore investigated whether rosiglitazone, an insulin-sensitizing drug that is known to improve endothelial dysfunction, was able to improve intrarenal endothelial dysfunction and microalbuminuria. Nineteen typ...