BACKGROUND There are many databases of small molecules focused on different aspects of research and its applications. Some tasks may require integration of information from various databases. However, determining which entries from different databases represent the same compound is not straightforward. Integration can be based, for example, on automatically generated cross-reference links betwe...

Humour plays an important role in human conversations. People use humour to keep a conversation pleasant, to provide some relaxation during a discussion and to cover up mistakes and misunderstandings. Embodied Conversational Agents (ECAs) that are able to understand and use humour will therefore be more believable and increase the motivation of a user to interact with them (Nijholt, 2005). Unti...

The Protein Identifier Cross-Reference (PICR) service is a tool that allows users to map protein identifiers, protein sequences and gene identifiers across over 100 different source databases. PICR takes input through an interactive website as well as Representational State Transfer (REST) and Simple Object Access Protocol (SOAP) services. It returns the results as HTML pages, XLS and CSV files...

MOTIVATION Metagenomes are often characterized by high levels of unknown sequences. Reads derived from known microorganisms can easily be identified and analyzed using fast homology search algorithms and a suitable reference database, but the unknown sequences are often ignored in further analyses, biasing conclusions. Nevertheless, it is possible to use more data in a comparative metagenomic a...

Reference charts are valuable tools for clinicians in their daily work on pediatric clinics. Reference charts are often constructed by smoothing techniques, and in this paper we present a newly developed non-parametric test for comparing these charts. We illustrate the method by two examples. The rst example compares crosssectional data on height in children from two Danish studies from 1970 an...

The state of art of positron emission tomography (PET) takes into account the accidental coincidence events and attenuation. The maximum likelihood estimator can handle this kind of random variation in the reconstruction of a PET image. However, the reconstruction is ill-posed and needs regularization. The boundary information, either from an expert or from the other medical modality of the sam...

Maximum likelihood estimate (MLE) is a widely-used approach for PET image reconstruction. However, it has been shown that reconstructing emission tomography based on MLE without regularization would result in noise and edge artifacts. In the attempt to regularize the maximum likelihood estimate , in this paper, we propose a new and eecient method to incorporate the correlated but possibly incom...

vernetziko is an assistive software tool primarily designed for managing cross-references in XML-based electronic dictionaries. In its current form it has been developed as an integral part of the lexicographic editing environment for the German monolingual dictionary elexiko developed and compiled at the Institut für Deutsche Sprache, Mannheim. This paper first briefly outlines how vernetziko ...

The importance of business related services has been growing consequently during the past years. Industrial Services constitute the greatest share of business related service with 30% of their intermediate output. But those kinds of services are facing tremendous challenges in terms of synchronizing their process with the manufacturing processes of their customers. The EU funded project InCoCo-...

Re-combining parts of existing 3D object models is an interesting and efficient technique to create novel shape collections. However, due to the lack of direct parts’ correspondence across different shape families, such data-driven modeling approaches in literature are mostly limited to the synthesis of inclass shapes only. To address the problem, this paper proposes a novel approach to create ...