OBJECTIVES To compare Telfa with the Rapid Rhino Riemann nasal pack for use following endoscopic sinus surgery. DESIGN Prospective, randomized, double-blind, paired trial. SETTING Tertiary otolaryngology hospital. PARTICIPANTS Forty-five adult patients undergoing bilateral endoscopic sinus surgery for either chronic rhinosinusitis or nasal polyps. MAIN OUTCOME MEASURES A visual analogue...

phadenopathy. Laboratory studies revealed a hematocrit of 18.3%, platelet count 118000/mm3, and leukocyte count of 5200/mm3 with 81% lymphoblasts, 1% myelocytes, 4% neutrophils and 14% lymphocytes. The bone marrow smear showed 95% blast cells. Intravenous piperacillin and gentamicin therapy was started on an empirical basis. After 10 days without response to the antibiotic regimen, he received ...

BACKGROUND Bacterial and viral respiratory tract infections may trigger relapses in patients with PR3-positive vasculitis. Data have suggested that treatment with co-trimoxazole may be beneficial, because this antibiotic could act by eliminating the offending microbe and thereby stopping the initiating stimulus. GOAL AND METHODS Prospective, randomized, placebo-controlled study of the efficac...

Fig 1. Photo-distributed eruption in a patient on simeprevir. The patient presented with a large erosion of the lower vermilion with honey-colored and hemorrhagic crusting (A) and ill-defined erythematous plaques with overlying tense bullae on the dorsolateral hands (B). INTRODUCTION Recently there has been a rapid evolution in the treatment of hepatitis C heralded by development of the direct-...

Processing substantially reduces the bioavailability of lysine in pet foods, and certain populations of cats may be at risk for deficiency. A previous study reported that kittens consuming lysine deficient diets developed facial skin lesions; however these were not characterized with histopathology. The hypothesis of this study was that kittens with lysine deficiency develop histopathologically...

Amenamevir is a potent helicase-primase inhibitor and a novel class of antiviral agent other than nucleoside compounds, such as aciclovir, valaciclovir and famciclovir. This study is the first randomized, double-blind, valaciclovir-controlled phase 3 study to evaluate the efficacy and safety of amenamevir in Japanese patients with herpes zoster when treated within 72 h after onset of rash. A to...

PENRITH, MARY-LOUISE & ROBINSON, J.T.R. 1996. Selenium toxicosis with focal symmetrical poliomyelomalacia in postweaning pigs in South Africa. Onderstepoort Journal of Veterinary Research, 63:171-179 An outbreak of paralysis in finisher pigs in South Africa after ingestion of feed containing 54,581 mg/kg of selenium is described. The main and entirely consistent lesion was bilaterally symmetric...

Surgical resection of lips is a relatively rare procedure. A defective lip may cause the patient to feel socially vulnerable as well as functionally handicapped and the defect will influence the patient's self-esteem and body image. Patients with labial defects also experience speech problems along with drying and crusting of the tissues in the area of defect. The lip and cheek provide a valve ...

Background. The objective of this prospective study was to evaluate the clinical profile, microbiological flora and radiological features in primary atrophic rhinitis patients and to identify their association with the etiology of primary atrophic rhinitis. Study design. Prospective case study. Materials and methods. Patients with primary atrophic rhinitis over a two years period were included ...

Imiquimod 5% cream (Aldara) was approved by the Food and Drug Administration for the treatment of non-facial superficial basal cell carcinomas (sBCC) in 2004 and has become one of the most commonly used topical treatments for this variant of basal cell carcinoma. Application of the cream once a day, 5 days per week for 6 weeks has demonstrated a clinical and histological cure rate approximating...