UNLABELLED Palmitoylation is an important post-translational lipid modification of proteins. Unlike prenylation and myristoylation, palmitoylation is a reversible covalent modification, allowing for dynamic regulation of multiple complex cellular systems. However, in vivo or in vitro identification of palmitoylation sites is usually time-consuming and labor-intensive. So in silico predictions c...

BACKGROUND Churg-Strauss syndrome (CSS) is a rare, systemic necrotising small and middle-sized vessel vasculitis, accompanied by blood eosinophilia, eosinophil infiltration of various tissues and bronchial asthma. Cardiac injury caused by myocardial eosinophilic infiltration and/or vasculitis in CSS seems to be very common. Active inflammatory process accompanied by myocardial fibrosis has been...

In comparison-shopping services (CSS), there exist frauds who perform excessive clicks on a target item in order to boost the popularity of it. In this paper, we introduce the problem of detecting frauds in CSS and propose three anomaly scores designed based on click behaviors of users in CSS.

The problem of finding the longest common subsequence (LCS) for a set of sequences is a very interesting and challenging problem in computer science. This problem is NPcomplete, but because of its importance, many heuristic algorithms have been proposed, such as Long Run algorithm and Expansion algorithm. However, the performance of many current heuristic algorithms deteriorates fast when the n...

In the paper the problem of General Shape Analysis (GSA) is investigated. It is similar to the recognition and retrieval of shapes. However, the analysed shape does not have to belong to any of the template classes. It is only similar to some of them. It may be said that the most general information about a shape is here concluded, namely how round, triangular, elliptical, etc. it is. This appr...

Churg–Strauss syndrome (CSS) is a systemic small-sized vessel vasculitis, characterised by severe asthma, transient pulmonary infiltrates, and blood and tissue eosinophilia [1]. CSS can affect several organs, including the lungs, heart, kidneys and peripheral nervous system. Anti-neutrophil cytoplasm autoantibodies (ANCA) mainly directed against myeloperoxidase (MPO) are detected in ,40% of pat...

This paper presents an educational tool which can be used for teaching the Simulated Annealing (SA) algorithm. The SA is applied to solve integrated circuit placement. SA is an effective method to solve NPcomplete problems as circuit placement. The interface developed in this work provides a visualization of the execution steps of the SA, which makes the tool more iterative and didactic. The to...