نتایج جستجو برای: cumulative index ipi and mcd
تعداد نتایج: 16869322 فیلتر نتایج به سال:
OBJECTIVE The purpose of this study was to determine contraceptive continuation and repeat pregnancy rates in adolescents who are offered immediate postpartum etonogestrel implant (IPI) insertion. STUDY DESIGN Participants in an adolescent prenatal-postnatal program were enrolled in a prospective observational study of IPI insertion (IPI group, 171) vs other methods (control group, 225). Cont...
BACKGROUND Both short and long interpregnancy intervals have been associated with an increased risk of adverse pregnancy outcomes. There is limited information about the impact of interpregnancy interval on pregnancy (IPI) outcomes in Tanzania. The objective of this study was to assess the effect of IPI on adverse pregnancy outcomes. METHODS We performed a retrospective cohort study using mat...
Results With a median follow-up of 17mo (range 0-9yr), the median OS for the entire cohort of 766 pts was 15mo, with a 2-yr OS of 41%. Of the 80 pts with OS ≥2 yrs post-Ipi for whom data are available, 75% (n = 60/80) remain alive and 30% (n = 24/80) remain progression-free following Ipi, with median Ipi disease control of 15mo (range: 3 to 107 +mo). Among pts with progression (n = 56), 57% exh...
soil contamination significantly reduces environmental quality and affects human health. to investigate and assess the effects of land use on the concentrations of some heavy metals in surface soils of golestan province, 227 soil samples (0-60 cm) were collected from three types of land uses including agricultural lands, natural, and industrial areas. the total metals and metalloids (cr, se, as...
مقدمه: حضور کارگاههای آلاینده محیط زیست خطرات بهداشتی را افزایش داده است. مطالعه حاضر با هدف ارزیابی آلایندگی ذرات غبار کف کارگاههای مکانیکی شهر یزد با فلزات سنگین صورت گرفته است. روشها: این پژوهش بهصورت تحلیلی-مقطعی در سال 1393 انجام شد. 30 کارگاه مکانیکی با روش نمونهبرداری تصادفی- طبقهبندیشده در شهر یزد انتخاب شد. پس از نمونهبرداری، نمونهها با دستگاه جذب اتمی (AAS) جهت تعیین فل...
Carbapenems are the primary choice of treatment for severe Pseudomonas aeruginosa infection. However, the emergence of carbapenem resistance due to the production of metallo-β-lactamases (MBLs) is of global concern. In this study, 90 imipenem- (IPM- or IP-) resistant P. aeruginosa (IRPA) isolates, including 32 previously tested positive and genotyped for MBL genes by PCR, were subjected to doub...
We report the crystal structure solution of the Intracellular Protease Inhibitor (IPI) protein from Bacillus subtilis, which has been reported to be an inhibitor of the intracellular subtilisin Isp1 from the same organism. The structure of IPI is a variant of the all-beta, immunoglobulin (Ig) fold. It is possible that IPI is important for protein-protein interactions, of which inhibition of Isp...
Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of nonalcoholic steatohepatitis. The ER stress response is activated in the livers of mice fed a methionine- and choline-deficient (MCD) diet, yet the role of ER stress in the pathogenesis of MCD diet-induced steatohepatitis is unknown. Using chemical chaperones on hepatic steatosis and markers of inflammation and fibrosi...
21 Background: Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of nonalcoholic 22 steatohepatitis. The ER stress response is activated in the livers of mice fed a methionineand choline23 deficient (MCD) diet yet the role of ER stress in the pathogenesis of MCD diet-induced steatohepatitis is 24 unknown. We aim to determine the effects of reducing ER stress using chemic...
MYC rearrangements occur in 5% to 10% of diffuse large B-cell lymphomas (DLBCL) and confer an increased risk to cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone (CHOP) and rituximab (R)-CHOP treated patients. We investigated the prognostic relevance of MYC-, BCL2- and BCL6-rearrangements and protein expression in a prospective randomized trial. Paraffin-embedded tumor samples from...
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