Autoimmune diseases affect 5-6% of the Caucasian population and represent a major burden on an individual’s life-style and the nation’s health budget. There have been no cures described with current treatment based on replacement therapy and/or broad immunosuppressive agents. A challenge for research in this field is to devise strategies aimed at specifically abrogating the immune response to s...

Abstract Background Oesophageal Cancer (OC) treatment levies substantial financial burden on Health Services and Best Supportive Care (BSC) outcomes are poor. Potentially Curative Surgery with or without Chemotherapy is offered to patients locally advanced disease this study aimed examine costs related life-years gained in having potentially curative (oesophagectomy) those receiving (BSC). Meth...

BACKGROUND UK policy guidance on treatment and care towards the end of life identifies a need to better recognise patients who are likely to be in the last 12 months of life. Health and social care professionals have a key role in initiating and managing a patient's transition from 'curative care' to palliative care. The aim of this paper is to provide a systematic review of evidence relating t...

The aim of the study was to investigate the association between depressive disorders and risk of tumor recurrence in patients with breast cancer after curative surgery.A nationwide cohort study between January 2001 and December 2007 was conducted. Data were taken from the Taiwan National Health Insurance Research Database. Among 30,659 newly diagnosed breast cancer patients, we identified 1147 ...

There is a growing concern in most countries to address the problem of inequities in health-care within the context of financial restraints on the public purse and the realities of health professions that are influenced strongly by the economic priorities of free-market economies. Dental professionals, like other health professionals, are well aware that the public expects oral health-related s...

Abstract Background Oral diseases place a significant burden on individual and population health. These are largely preventable; health promotion initiatives have been shown to decrease the disease rates. However, there is limited implementation of in dentistry, this could be due number factors; ethos philosophy dentistry focused curative, individualised approach oral diseases, confusion around...