Abstract Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. The major objective of this study is over- production of recombinant human insulin-like growth factor I( rhIGF-I) through a developed process by recruiting effective factors in order to achieve the most recombinant protein. Up to now E. coli expression system has been widely us...

Abstract Human insulin-like growth factor I (hIGF-I) is a kind of growth factor with clinical significance in medicine. The major objective of this study is over- production of recombinant human insulin-like growth factor I( rhIGF-I) through a developed process by recruiting effective factors in order to achieve the most recombinant protein. Up to now E. coli expression system has been widely us...

Anchovy fillets that had undergone osmotic dehydration and response surface methodology (RSM) were used to determine the influence and optimal values of the process variables. Also the optimal processing conditions were determined in order to reduce the solid gain and water loss ratio (SG/WL) and firmnessfor the anchovy fillets. A three-levelcentral composite rotatabledesign (CCRD) involving th...

The modern engineering design optimization process often replaces laboratory experiments with computer simulations, which leads to expensive black-box optimization problems. Such problems often contain candidate solutions which cause the simulation to fail, and therefore they will have no objective value assigned to them, a scenario which degrades the search effectiveness. To address this, this...

Engineering design optimization using concurrent integrated experiment and simulation is a Dynamic Data Driven Application System (DDDAS) wherein remote experiment and simulation can be synergistically utilized in real-time to achieve better designs in less time than conventional methods. The paper describes the Data Driven Design Optimization Methodology (DDDOM) being developed for engineering...

Presented a new hybrid particle swarm algorithm based on P systems, through analyzing the working principle and improved strategy of the elementary particle swarm algorithm. Used the particles algorithm combined with the membrane to form a community, particles use wheel-type structure to communicate the current best particle within the community. The best particles, as Representative, compete f...