In this study, we introduce a new type of surface curves called $D$-type curve. This curve is defined by the property that the unit Darboux vector $vec{W}_{0} $ of a surface curve $vec{r}(s)$ and unit surface normal $vec{n} $ along the curve $vec{r}(s)$ satisfy the condition $leftlangle vec{n} ,vec{W}_{0} rightrangle =text{constant}$. We point out that a $D$-type curve is a geodesic curve or an...

BACKGROUND The expending and invasive features of tumor nests could reflect the malignant biological behaviors of breast invasive ductal carcinoma. Useful information on cancer invasiveness hidden within tumor nests could be extracted and analyzed by computer image processing and big data analysis. METHODS Tissue microarrays from invasive ductal carcinoma (n = 202) were first stained with cyt...