วารสารโลหติวทิยาและเวชศาสตร บรกิารโลหติ ป ที ่12 ฉบบัที ่4 ตลุาคม-ธนัวาคม 2545 must be considered in the differential diagnosis of an anterior mediastinal mass.1 The majority of mediastinal masses in this age group are malignant, mostly Hodgkins and NonHodgkins lymphoma.2 Less than 5% of mediastinal masses are of thymic origin. We report Case Report Massive Thymic Hyperplasia Mimicking Lymphoma:...

The pharmacokinetics of cyclophosphamide was studied in 10 Kenyan Africans with Hodgkins lymphoma. The mean +/- s.d. elimination half-life (t1/2) was 7.5 +/- 1.38 h. The mean +/- s.d. volume of the central compartment (V1) was 0.35 +/- 0.12 l/kg and the apparent volume of distribution (V) was 0.64 +/- 0.06 l/kg. The microconstants k21, k12 and k10 were 1.81 +/- 0.84 h-1, 1.90 +/- 1.080 h-1 and ...

BACKGROUND Subacute cutaneous lupus erythematosus is a nonscarring, non-atrophy-producing photosensitive cutaneous disorder. Half of the patients have 4 or more of the criteria for classification as systemic lupus erythematosus. In some patients, drugs induce or exacerbate the cutaneous disease. OBSERVATION We describe 5 patients who had either an exacerbation or a new onset of subacute cutan...

In common rheumatologic diseases skin findings are an important diagnostic clue for astute clinicians. Skin manifestations can help identify systemic disease or may require therapy uniquely targeted at the cutaneous problem. This article discusses 3 common rheumatologic conditions seen in adults by dermatologists: cutaneous lupus, dermatomyositis, and morphea. The focus is on the cutaneous find...

background and objectives: classic hodgkin lymphoma (chl), anaplastic large cell lymphoma (alcl) and some cases of diffuse large b cell lymphoma (dlbcl) have overlapping morphologic features. since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. materials and methods: we included 61 cases ...

background : cutaneous leishmaniasis is one of the prevalent health problems in tropical and subtropical areas including iran. therefore, it is essential to identify the prevalence and new foci of this disease in different regions of iran. this study aimed to determine the epidemiology of cutaneous leishmaniasis by active surveillance in elementary schools in pakdasht city, southeast of tehran,...

Background: Accurate diagnosis of cutaneous leishmaniasis wouldavoid unnecessary treatment and scar formation. Direct smear isthe most common method for the diagnosis of this disease but itsnegative result could not rule out the infection; so, the need formore sensitive methods is obvious. We conducted this study tocompare the efficiency of direct skin smear with smears preparedby fine needle a...