Background: Melanoma is a malignant neoplasia that shows high mortality when diagnosed in advanced stages. Early identification of high-risk patients for the development of melanoma metastases is the main strategy to reduce mortality. oBjective: To assess the influence of eight epidemiological and histopathologic features on the development of metastases in patients diagnosed with primary cutan...

Dermatol Sinica, June 2005 From the Departments of Dermatology, Radiation Oncology and Pathology, Far Eastern Memorial Hospital; Department of Pathology, National Taiwan University Hospital, Department of Radiation Oncology, National Defense Medical Center Accepted for publication: January 26, 2005 Reprint requests: Ying-Jui Chang, M.D., Department of Dermatology, Far Eastern Memorial Hospital,...

OBJECTIVE To characterize clinical presentation and prognostic factors in patients with histologically proven regional lymph node metastasis from cutaneous squamous cell carcinoma of head and neck origin. DESIGN Retrospective, nonrandomized case series. SETTING Tertiary referral center. PATIENTS Forty-five patients treated between 1984 and 1995 with regional metastatic squamous cell carci...

ER: estrogen receptor IMDC: intramammary ductal carcinoma PCAC: primary cutaneous apocrine carcinoma PR: progesterone receptor INTRODUCTION Primary cutaneous apocrine carcinoma (PCAC) is a rare cutaneous adnexal tumor that presents a diagnostic challenge, with histology and staining mirroring those seen in mammary ductal carcinoma and other adnexal neoplasms. We report the first case, to our kn...

The diagnosis of cutaneous melanoma in situ, considered to have excellent prognosis, has been increasingly frequent, with rare isolated reports of cutaneous melanoma in situ presenting recurrence, metastasis, and death. No specific study is found in the literature about these lesions of unexpected behavior. We describe the demographic and histopathological findings of 448 cases of cutaneous mel...

Cutaneous neuroendocrine carcinoma, first described in 1972, is an aggressive disease usually occurring in sun-exposed skin. Other sites have been described, however; such tumors occasionally occur within the nasal fossa. A high rate of metastasis (>30%) explains the poor prognosis. Descriptions of the imaging features of these tumors, mainly located in cutaneous region, are rare. We therefore ...

Cutaneous metastasis from internal malignancies are rare with a reported incidence between 0.7% and 10%. The most common tumor that metastasize to the skin is breast cancer. We present a 53-year-old woman with a history of bilateral breast cancer who underwent FDG-PET/CT for re-staging, which demonstrated isolated cutaneous and subcutaneous chest wall metastases. Histopathologic verification co...