The peculiar versatility of remotely enolizable 6-methyluracil-5-carbaldehydes as useful vinylogous pronucleophiles in direct, asymmetric [4+2] cyclizations with suitable nitroolefins has been demonstrated. Under the strategic exploitation noncovalent bifunctional organocatalysis, a dearomative remote enolization strategy was implemented, to generate oQDM-type dienolate intermediates that were ...

Abstract Herein, we present a novel approach for various asymmetric transformations of cyclic enones. The combination readily accessible chiral diamines and sterically demanding flexible phosphoric acids resulted in simple highly tunable catalyst framework. careful optimization the components led to identification particularly powerful multi‐purpose organocatalyst, which was successfully applie...

Novel nitrogen-bridged diazocines (triazocines) were synthesized that carry a formyl or an acetyl group at the CH 2 NR-bridge and bromo- iodo-substituents distant phenyl ring. The photophysical properties investigated in acetonitrile water. As compared to previous approaches yields of intramolecular azo cyclizations increased (from ≈40 60%) using oxidative approach starting from corresponding a...