The threshold for cough induced by inhaled tartaric acid was measured in 71 non-atopic healthy volunteers. The cough threshold was lower in women than in men, which may be relevant to previous reports that angiotensin converting enzyme inhibitors induce cough more frequently in women than in men.

A novel domino synthesis of 1,3,5-trisubstituted hydantoin derivatives has been developed in low melting L-(+)-tartaric acid-DMU melt mixtures. The functionalized hydantoins are obtained in good yields from β,γ-unsaturated ketoacids and urea under environmentally benign and simple reaction conditions.

The rates of adsorption of three commercial reactive dyes and Cu(II) from water in the absence and presence of complexing agents using chitosan were measured at 308C. Three simplified kinetic models, i.e., pseudo-first-order, pseudo-second-order, and intraparticle diffusion, were tested to investigate the adsorption mechanisms. It was shown that the adsorption of reactive dyes and Cu(II) in the...

Paclitaxel-coated balloons (PCBs) have become effective treatment options for vascular disease, but long-term drug release and biocompatibility are influenced by the patterns. In this work, paclitaxel coatings were prepared via electrostatic spraying, effect of D-tartaric acid additives was investigated. Microstructures surface morphology studied using Fourier transform infrared spectroscopy (F...

In the crystal structure of the title compound {alternative name: 1-[1-(2-hydroxy-phen-yl)ethyl-ideneamino]-3-(1H-indol-3-ylmethyl-eneamino)urea}, C(18)H(17)N(5)O(2), the planar indole component is twisted at an angle of 63.7 (10)° with respect to the rest of the mol-ecule. This compound is one of a series being studied for biological activity. The hydr-oxy groups are involved in both intra-mol...

In an earlier study of the effect of culture of excised tobacco leaves in darkness in solutions of a number of common organic acids (1)) it was noted that the behavior of the malic and citric acids in leaves cultured in (+)tartrate differed little if at all from that observed in the control samples cultured in solutions of inorganic salts. However, the so called “unknown acid” fraction, i.e. th...

Objective: The aim of this preliminary study was to investigate gel forming of Makjong powder in effervescent blend and evaluate the probability to develop Makjong effervescent powder formulation for medicinal and beverage applications. Methods: Blank effervescent blend consisted of citric acid, tartaric acid, and sodium bicarbonate with different ratio was prepared. The effervescent blends wer...

The improved performance of the sparteine surrogate compared to sparteine in a range of applications has highlighted the need to develop an approach to the (-)-sparteine surrogate, previously inaccessible in gram-quantities. A multi-gram scale, chromatography-free synthesis of the racemic sparteine surrogate and its resolution via diastereomeric salt formation with (-)-O,O'-di-p-toluoyl-l-tarta...

Background: Antiseptic products that are widely found in the market contain chloroxylenol which can cause irritation and allergic reactions when used frequently. In addition, antiseptic liquid form considered less practical economical. The alternative to overcome these problems is utilize natural ingredients made solid dosage forms of effervescent tablets. One plant has potential as an papaya l...