I Drillien, C M, Developmental Medicine and Child Neurology, 1972, 14, 563. 2 Davies, P A, and Tizard, J P M, Developmental Medicine and Child Neurology, 1975, 17, 3. 3 Stewart, A L, et al, Archives of Disease in Childhood, 1977, 52, 97. 4Committee on Child Health Services, Fit for the Fuiture. London, HMSO, 1976. (Court Report.) 5 Chamberlain, R, et al, British Births 1970, vol 1. London, Hein...

A new withanolide, named withawrightolide (1), and four known withanolides (2-5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withametelin L (2) was confirmed by X-ray crystallographic analysis. Using MTS viability assays, withanolides 1-5 showed antiproliferati...

Plant tissue culture techniques were used to study the effect of NaCl on tropane alkaloids accumulation and proline content of both Datura metel and Datura stramonium. Callus cultures were established for both Datura species. However, MS medium supplemented with 1mg/l of both BA and NAA was the best for callus production in D. metel, while MS supplemented wit...

Thorn Apple or Jimson Weed (Datura stramonium) is a tropane alkaloid containing widespread pest plant growing in central Europe. This predominantly occurs millet, buckwheat and maize cultivation. Therefore, sound cleaning of these crops just as pivotal reliable analytics. The millet at laboratory scale with commercial mechanical devices, such sieves, indented separators table sorters without us...

Selection exerted by herbivores is a major force driving the evolution of plant defensive characters such as leaf trichomes or secondary metabolites. However, plant defense expression is highly variable among populations and identifying the sources of this variation remains a major challenge. Plant populations are often distributed across broad geographic ranges and are exposed to different her...