Members of the large Sec7 domain-containing Arf guanine nucleotide exchange factor (GEF) family have been shown to dimerize through their NH2-terminal dimerization and cyclophilin binding (DCB) and homology upstream of Sec7 (HUS) domains. However, the importance of dimerization in GEF localization and function has not been assessed. We generated a GBF1 mutant (91/130) in which two residues requ...

Sharikabad, Mohammad N., Kirsten M. Østbye, Torstein Lyberg,and Odd Brørs. Effect of extracellular Mg on ROS and Ca accumulation during reoxygenation of rat cardiomyocytes. Am J Physiol Heart Circ Physiol 280: H344–H353, 2001.—The effects of Mg on reactive oxygen species (ROS) and cell Ca during reoxygenation of hypoxic rat cardiomyocytes were studied. Oxidation of 29,79-dichlorodihydrofluoresc...

In this paper, the fatigue and fracture properties of bovine dentin are evaluated using in vitro experimental analyses. Double cantilever beam (DCB) specimens were prepared from bovine maxillary molars and subjected to zeroto-tension cyclic loads. The fatigue crack growth rate was evaluated as a function of the dentin tubule orientation using the Paris law. Wedge-loaded DCB specimens were also ...

Aromatic amines, such as benzidine and 3,3'-dichlorobenzidine (DCB), are part of the dyes and pigments manufacturing process. The prolonged use of these carcinogenic chemicals in the past generation has introduced a significant amount of contamination to the environment. Their persistency in several mediums has sparked a number of studies in an attempt to develop predictive tools of their fate ...

The ability to predict rates of contaminant sorption and desorption in the environment is essential in order to determine contaminant bioavailability, predict contaminant fate and transport, and assess risk. In this paper, we present a new method to determine sorption-desorption time scales from the temporal moments of batch experimental data. Here, the term time scale has a precise meaning: Ti...

SEE PAGE 1072 D espite significant improvements in clinical outcomes of patients suffering from femoropopliteal peripheral artery disease treated with drug-eluting technologies, dedicated bare-metal stent designs, and atherectomy endovascular technologies (1–8), durability of endovascular treatment of longer infrapopliteal lesions remains one of the last significant challenges (9–11). In this i...

Graphene is a single layer of graphite with hexagonal structure which have stacked layers. has recently been recognized by its researchers due to it sp2 bonds in lattice, the two-dimensional atomic thickness, and superior electrical, electrochemical, optical, thermal, mechanical properties lightness. Liquid phase exfoliation (LPE) most promising method graphene research produce high quality pro...