Tat activates human immunodeficiency type 1 gene expression by binding to TAR RNA. TAR comprises a partially base paired stem and hexanucleotide loop with a tripyrimidine bulge in the upper stem. In vitro, Tat binds to the bulge and upper stem, with no requirement for the loop. However, in vivo, loop sequences are critical for activation, implying that a loop binding cellular factor may be invo...

OBJECTIVES The aim of this study was to investigate the relation between work-family conflict and burnout, and the mediating role of psychological capital (PsyCap) in the relation between work-family conflict and burnout, among Chinese doctors. METHODS This cross-sectional study was performed during the period of September/October 2010. A questionnaire that comprised work-family conflict asse...

We propose a novel restoration method for defects and missing regions in video sequences, particularly in application to archive film restoration. Our statistical framework is based on random walks to examine the spatiotemporal path of a degraded pixel, and uses texture features in addition to intensity and motion information traditionally used in previous restoration works. The degraded pixels...

PT. Keramik Diamond Industries (KDI) merupakan perusahaan yang bergerak dibidang industri keramik dinding dan lantai. Dalam tahapan proses produksinya masih sering terjadi berbagai penyimpangan serta hambatan dapat mengakibatkan produk ubin (tile) dianggap cacat. Produk tile dianggab cacat produksi berupa : gupil sesudah glaze, bakar, sebelum retak body kotor affal. Sebagai upaya untuk menurunk...

We present an analysis of the hot pixel population in ACS CCDs. The number of hot pixels increases due to on-orbit radiation damage. In order to heal the defects responsible for the hot pixels, the CCDs are heated once a month. We review the effectiveness of the anneal process.

Compensatory growth (CG) may be an adaptive mechanism that helps to restore an organisms' growth trajectory and adult size from deviations caused by early life resource limitation. Yet, few studies have investigated the genetic basis of CG potential and existence of genetically based population differentiation in CG potential. We studied population differentiation, genetic basis, and costs of C...

Two of the antigenic characters of erythrocytes, that in either identical or related forms differentiate four species of Streptopelia (chinensis, humilis, orientalis, and senegalensis) from a fifth (S. risoria) by interaction of the causative genes, are involved in the appearance in backcross hybrids of additional antigenic specificities to those of the parental species. The cells of backcross ...

"HIV controllers" (HICs) are rare individuals in whom HIV-1 plasma viral load remains undetectable without antiretroviral treatment. This spontaneous viral control in HICs is usually associated to strong functional HIV-specific CD8(+) T cell responses. Accordingly, we have recently shown that CD8(+) T cells from HICs strongly suppress ex vivo HIV-1 infection of autologous CD4(+) T cells, sugges...

To appreciate the Portuguese circumstances concerning situations of obstetric medico-legal conflicts and to evaluate the influence of the quality of files in expert conclusions, an analysis of all cases of obstetric medical responsibility from 2001-11 was carried out. File quality was evaluated by absence or insufficiency of clinical information supplied, by poor quality of document copies and ...

Coronaviruses contain a very large RNA genome, which undergoes recombination at a very high frequency of nearly 25% for the entire genome. Recombination has been demonstrated to occur between viral genomes and between defective-interfering (DI) RNAs and viral RNA. It provides an evolutionary tool for both viral RNAs and DI RNA and may account for the diversity in the genomic structure of corona...