Ataxia-Telangiectasia (AT) is a rare human neurodegenerative autosomal recessive multisystem disease that is characterized by a wide range of features including, progressive cerebellar ataxia with onset during infancy, occulocutaneous telangiectasia, susceptibility to neoplasia, occulomotor disturbances, chromosomal instability and growth and developmental abnormalities. Mitochondrial DNA (mtDN...

Indexed constraints (like cophonologies) increase a grammar’s fit to seen data, but do they hurt the ability generalize unseen data? We focus on French schwa deletion, an optional process whose rate of application is modulated by both phonological and lexical factors, we propose three indexed constraint learners in Maximum Entropy (MaxEnt) framework. Using data from Racine (2008), test four cap...

The coordination of gestures in consonant clusters differs across languages and hence must be a learned aspect linguistic knowledge. Precisely pinning down the relation used particular language, or for cluster type, has been facilitated by recent research showing that relations structure kinematic variation unique ways. We apply these methods to hitherto under-explored topic, created via vowel ...

Due to the advantages of high information densities and longevity, DNA storage systems have begun attract a lot attention. However, common obstacles are caused by insertion, deletion, substitution errors occurring in synthesis sequencing. In this paper, we first explain method convert binary data into general maximum run-length $r$ sequences with specific length construction, which can be used ...

cFLIP is required for epidermal integrity and skin inflammation silencing via protection from TNF-induced keratinocyte apoptosis. Here, we generated analyzed KO mice with additional TNF deficiency. Intriguingly, the ablation of rescued pathological phenotype characteristic weight loss increased mortality. Moreover, lack in these animals strongly reduced delayed hyperkeratosis apoptosis keratino...

Reduced expression of the plasma membrane citrate transporter INDY (acronym I’m Not Dead, Yet) extends life span in lower organisms. Deletion mammalian Indy (mIndy) gene rodents improves metabolism via mechanisms akin to caloric restriction, known blood pressure (BP) by sympathoadrenal inhibition. We hypothesized that mIndy deletion attenuates support BP. Continuous arterial BP and heart rate (...

In this note, we investigate listing cliques of arbitrary sizes in bandwidth-limited, dynamic networks. The problem detecting and triangles was originally studied great detail by Bonne Censor-Hillel (ICALP 2019). We extend study to graphs where more than one update may occur as well resolve an open question posed (2019). Our algorithms results are based on some simple observations about under v...