Treatment of a traumatically intruded maxillary incisor with an immature apex remains controversial. Treatment options include observation, surgical repositioning, or orthodontic forced eruption. Likewise, the ideal timing of surgical removal of a mesiodens is highly controversial: immediate versus delayed intervention. The complications associated with untreated supernumerary teeth include: ov...

Apical periodontitis is an inflammatory disorder of periradicular tissues caused by aetiological agents of endodontic origin. The subject has been reviewed by Nair. (1)(2) They are believed to result from inflammatory processes in the periapical tissues associated with bacterial infection and necrosis of the dental pulp in carious teeth. As a consequence of these processes and the inability of ...

Dens invaginatus is a malformation of teeth probably resulting from an infolding of the dental papilla during tooth development. Affected teeth show a deep infolding of enamel and dentine starting from the foramen coecum or even the tip of the cusps, and which may extend deep into the root. Teeth most affected are maxillary lateral incisors and bilateral occurrence is not uncommon. The malforma...

The objective of this study was to compare the effect of prophylactic amoxicillin used and placebo in preventing endodontic flare-up in teeth with asymptomatic necrotic pulp and periradicular pathosis undergoing root canal treatment. The Quasi experimental study on 125 patients formed the study groups which was conducted at the Department of Operative Dentistry of Khyber College of Dentistry, P...

Lysophosphatidic acid (LPA) is a locally produced bioactive phospholipid which is involved in tissue repair. The objective of this study was to determine whether dental pulp tissue also responds to the phospholipid. Effects of LPA on proliferation, differentiation, and mitogen-activated protein kinase (MAPK) signaling of dental pulp fibroblasts (DPF) were examined in vitro. We report that DPF e...

The purpose of this study was to investigate dentin-bridge formation in teeth following the transplantation of dental pulp-derived cells seeded on hydroxyapatite/tricalcium phosphate (HA/TCP) scaffolds. The dental pulp tissues were removed from the extracted first molar teeth of miniature pigs and single cell populations were subcultured. Second-passage cells that had alkaline phosphatase activ...

Teeth have been recognized as providing a useful long-term record of lead (Pb2+) uptake. However, information regarding the effects of lead on dental pulp tissue cells that foster dentinogenesis is scarce. This study investigated the effects of lead on dental pulp tissue using human dental pulp fibroblasts in vitro. Dental pulp cells from the teeth of young patients (aged 17-24 years) were cult...

AIM The aim of the present study was to systematically review the influence of orthodontic force on human dental pulp. METHODS AND RESULTS The addressed focused question was "Do orthodontic forces affect the human dental pulp?" which was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a specific question was constructed according to the PIC...