Selecting the appropriate anesthetic protocol for the individual animal is an essential part of laboratory animal experimentation. The present study compared the characteristics of four anesthetic protocols in mice, focusing on the vital signs. Thirty-two male ddY mice were divided into four groups and administered anesthesia as follows: pentobarbital sodium monoanaesthesia; ketamine and xylazi...

BACKGROUND Sufentanil and alfentanil have pharmacokinetic and dynamic properties which make them favourable substances for total intravenous anesthesia (TIVA) in combination with propofol. OBJECTIVES We planned to compare two clinical protocols for TIVA with propofol, and either sufentanil or alfentanil in regards to postoperative pain, hemodynamic stability during the case and time for emerg...

background: calcium (ca+2) plays an important role in many biophysiological mechanisms .the present study was carried out to assess alterations in total serum calcium level before and after operations in consider to the type of anesthesia. materials and methods: this descriptive study was conducted on 74 women who candidate for gynecological abdominal operations during one year at al-zahra mate...

Aims of Study In the case of tension-free vaginal tape (TVT) surgery, muscle strength is required for obtaining an adequate increase in abdominal pressure when conducting a stress test by coughing during the procedure. Consequently, although the procedure is frequently performed under local infiltration anesthesia, this requires the use of a large amount of local anesthetic. We employ the use o...

BACKGROUND Currently, patients older than 60 years of age represent 25% of the population and are at an increased risk during surgery. Therefore, reducing postoperative morbidity and mortality is a major concern in medical research and practice. Dependence on caregivers and cognitive impairment represent two major risk factors in the elderly, especially in frail patients after surgery under gen...

BACKGROUND This study was planned to determine the relationship between bispectoral index (BIS) during dental treatment and recovery conditions in children undergoing two regimes of anesthesia of propofol and isoflurane. MATERIALS AND METHODS In this single-blind clinical trial study, 57 4-7-year-old healthy children who had been referred for dental treatment under general anesthesia between ...

The majority of ophthalmic procedures are performed under regional anesthesia, but the proximity of important structures such as the blood vessels, optic nerve and the brainstem lead to increased risks associated with these blocks. The most serious of these complications is brainstem anesthesia. As the number of outpatient freestanding surgical centers increase, the significance of these potent...

Direct current auditory evoked potentials (DC-AEPs) are a sensitive indicator of depth of anesthesia in animals. However, they have never been investigated in humans. To assess the potential usefulness of DC-AEPs as an indicator of anesthesia in humans, we performed an explorative study in which DC-AEPs were recorded during propofol and methohexital anesthesia in humans. DC-AEPs were recorded v...

Autistic children are very difficult to manage in the hospital setting because they react badly to any change in routine. We describe a case of 10-year-old male patient with severe autism undergoing orchidopexy and circumcision. Following premedication, anesthesia was induced with remifentanil, propofol, atracurium, and maintained with total intravenous anesthesia (propofol and remifentanil). T...