Diabetes can be simply classified into type 1 diabetes mellitus and type 2 diabetes mellitus. Zinc transporter 8 (ZnT8), a novel islet autoantigen, is specifically expressed in insulin-containing secretory granules of β-cells. Genetic studies show that the genotypes of SLC30A8 can determine either protective or diabetogenic response depending on environmental and lifestyle factors. The ZnT8 pro...

BACKGROUND/AIMS Diabetes is well-known to influence endothelial function. Endothelial function and blood flow regulation might be different in diabetic and non-diabetic pregnancy. However, the impact of umbilical blood flow regulation in gestational diabetes on fetal development is unknown so far. METHODS In a prospective birth cohort study, we analyzed the association of the umbilical artery...

OBJECTIVE To assess the relationship between low maternal serum 25-hydroxyvitamin D levels and gestational diabetes mellitus in Turkish pregnant women according to the severity of 25-hydroxyvitamin D deficiency and assess intact parathyroid hormone levels in women with gestational diabetes mellitus and controls with low and sufficient 25-hydroxyvitamin D levels. METHODS We analyzed serum 25-h...

Concurrent disorders with diabetes mellitus is one of the most challenging subject. Our knowledge of the most common concurrent disorders in diabetic dogs may be useful in diagnosis of these disorders and better treatment of diabetic dogs. In this study diabetes mellitus was diagnosed in a 7-year-old male German shepherd dog, based on clinical and laboratory findings. Following the diagnosis of...

during last decades many researchers have focused on the conditions associated with bell's palsy including diabetes mellitus, hypertension, and viral infections. this study was performed to evaluate correlation of diabetes mellitus and bell's palsy and some relevant features not discussed in the literature in an iranian population. the presence of diabetes mellitus was evaluated in a total numb...

Diabetes mellitus is very rare in infants. Cases in recent years have been reported by Schwartzman, Crusius and Beirne (1947), by Bertoye and Stefani (1954) and by Keidan (1955), who reviewed the hitherto published cases of infantile diabetes. In Keidan's report 79 cases of infantile diabetes are mentioned, the neonatal cases attracting special interest on account of certain clinical characteri...

insulinoma in a patient with pre-existing diabetes is extremely rare. only a small number of cases have been reported all over the world. we report a case of insulinoma in a patient with type 2 diabetes. a 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, ...