in pregnant mothers maternal diabetes happens when the pancreas cannot produce enough insulin, soblood glucose increases in the mother and then in the fetus, resulting in several injuries in neonates. thisstudy was conducted to evaluate the effects of maternal diabetes on fetal cerebrum. sixteen adult female rats were divided in two equal groups. diabetes was induced in one group by alloxan. bo...

BACKGROUND Maternal diabetes mellitus in pregnancy results in greater offspring adiposity at birth. It is unclear whether it is associated with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or shared familial characteristics. METHODS AND RESULTS A record-linkage prospective cohort study of 280,866 singleton-born Swedish men from 248,293 families was ...

M aternal diabetes before pregnancy is associated with adverse maternal and perinatal outcomes, including acquired hypertension during pregnancy (1–3). The maternal placental syndromes preeclampsia and abruption or infarction of the placenta (4) are also more prevalent in women with insulin resistance, diabetes, and the metabolic syndrome (3,5–8). We evaluated the risk of placental vascular dis...

OBJECTIVE Women with diabetes in pregnancy have high rates of pregnancy complications. Our aims were to explore trends in the incidence of diabetes in pregnancy and examine whether the risk of serious perinatal outcomes has changed. RESEARCH DESIGN AND METHODS We performed a population-based cohort study of 1,109,605 women who delivered in Ontario, Canada, between 1 April 1996 and 31 March 20...

Although insulin remains the standard medication for the treatment of all types of patients with diabetes during pregnancy, oral hypoglycemics may be considered as alternative medications in the treatment of some types of diabetes in pregnancy.

Diabetes mellitus is one of the commonest pre-existing medical disorders complicating pregnancy in the UK. Having either type 1 or type 2 diabetes increases the likelihood of poor pregnancy outcomes. Here we review specific advice women with diabetes should receive before conception to help reduce such risks.

Gestational diabetes mellitus (GDM) is the most common medical complication of pregnancy today. As per American Diabetes Association (ADA) 2022, latest definition GDM diagnosed in second or third trimester that was not clearly overt prior to gestation. Blood sugar more than normal and less first defined as hyperglycemia early pregnancy. has been associated with adverse effects outcomes such pre...

OBJECTIVE The offspring of mothers who had diabetes during pregnancy experience increased risk later of diabetes and obesity later. We hypothesized that, in light of the historical improvements in the management of diabetes during pregnancy, these late consequences of the early environment might be diminishing with time. RESEARCH DESIGN AND METHODS Birth weight and information on BMI and gluc...