We have studied a new sample of 276 NIDDM patients from the population of Penne (Italy). Comparison of the new data with those of 214 diabetic pregnant women from the population of Rome reported in a previous paper has shown that the pattern of association between low molecular weight acid phosphatase genotype and degree of glycemic control is similar in the two classes of diabetic patients. Am...

About 6 to 8 percent of all pregnancies, especially primigravidae is complicated by preeclampsia, a classical triad of elevated blood pressure, proteinuria and edema. Maternal and neonatal morbidity and mortality are of utmost concern as the etiology of preeclampsia is uncertain. At-risk pregnant women can be suspected if they are primigravidae, multiparous, obesed, diabetic, hypertensive, or i...

The number of pregnant women who have type 2 diabetes and the number found to have gestational diabetes are progressively increasing. In the future, as many as 20% of pregnant women may be diagnosed with diabetes. Although there is consensus regarding many issues in the treatment of pregnant women with diabetes, there are few evidenced-based studies upon which to base the timing of delivery. Th...

INTRODUCTION Despite tight glycemic control, pregnancy complication rate in type 1 diabetes patients is higher than in normal pregnancy. Other etiological factors may be responsible for the development of adverse pregnancy outcome. Acceptance of the semi-allogeneic fetus is accompanied by adaptations in the maternal immune-response. Maladaptations of the immune-response has been shown to contri...

OBJECTIVE To evaluate the prevalence of diabetic nephropathy and microalbuminuria in pregnant women with type 2 diabetes in comparison with type 1 diabetes and to describe pregnancy outcomes in these women following the same antihypertensive protocol. RESEARCH DESIGN AND METHODS Among 220 women with type 2 diabetes and 445 women with type 1 diabetes giving birth from 2007-2012, 41 women had d...

Serum uric acid (SUA) and ascorbic acid levels were evaluated in 40 patients preclampsia [18-diabetic pre-eclamptic women (DM-PRW) & 22 without diabetes (PRW)]; 20 normotensive pregnant women [8 with gestational diabetes (G-DM) & rest 12 were healthy pregnant women (HPW)]; and control group consisting of 20 healthy non-pregnant women. SUA values were significantly increased in PRW & DM-PRW as c...

Diabetes occurring in association with pregnancy is a condition of the utmost gravity. It is one fraught with danger to both mother and child, and, in dealing with it, the skill of the obstetrician and of the physician may be alike put to the test. Fortunately, the complication is a rare one, for diabetes exerts an unfavourable influence upon the reproductive functions, giving rise at first to ...

BACKGROUND Metabolic syndrome (MetS) is a cluster of risk factors for type 2 diabetes (Type2 DM) and cardiovascular diseases (CVD), and its prevalence varies based on region, population, and sex. Newborns of women with MetS have a greater risk of adverse perinatal outcomes. This study explores the prevalence of metabolic syndrome in non-diabetic, pregnant Angolan women and the adverse perinatal...

The concentrations of C-peptide and phosphatidylglycerol in the amniotic fluid were determined in 36 pregnant diabetic women. Twenty-one patients who were being treated with insulin for gestational diabetes as well as 15 patients who were insulin dependent were studied. All patients were subjected to a program of strict metabolic control, and amniocentesis was performed at gestational week 36-3...