Results of cholinesterase, dibucaine and fluoride numbers, and scoline hydrolysis rates are presented in a family found to have normal, silent and abnormal genes for plasma cholinesterase. Five sibs, confirmed by red cell grouping and tissue typing, have been shown to possess a cholinesterase pattern which cannot be explained on the basis of accepted theories of inheritance. In view of this it ...

BACKGROUND Numerous studies have implicated spinal extracellular signal-regulated kinases (ERKs) as mediators of nociceptive plasticity. These studies have utilized pharmacological inhibition of MEK to demonstrate a role for ERK signaling in pain, but this approach cannot distinguish between effects of ERK in neuronal and non-neuronal cells. The present studies were undertaken to test the speci...

In this paper, a comprehensive numerical study is presented for the fully developed two-dimensional flow of viscous incompressible fluid through a curved duct with square cross section. Numerical calculations are carried out over a wide range of the Dean number 6500 100   Dn for the curvature 5 . 0   . A temperature difference is applied across the vertical sidewalls for the Grashof number ...

Exercise is recommended for the management of type 2 diabetes, but its effects on diabetic nephropathy (DN) are still unknown. We hypothesized that appropriate exercise improves early DN via attenuation of inflammation and oxidative damage. Type 2 diabetic KK-A(y) mice, a spontaneous DN model, underwent two different kinds of exercise (i.e., moderate and low intensity). Sedentary mice or those ...

In 1946, Paul Erdős proposed the following problem: what is the maximum number of unit distances among n points in the plane? Erdős established an upper bound of cn3/2 and a lower bound that grows slightly faster than n. A graph is a collection of “vertices” and “edges” connecting some pairs of vertices. For example, in an airline route chart, airports are the vertices and direct connections co...

AIMS/INTRODUCTION Patients with diabetic nephropathy (DN) typically show varying degrees of proteinuria and renal impairment. Because these clinical signs are frequently observed in other glomerulopathies, renal biopsy is required to make a definitive diagnosis of DN. We carried out the present study to evaluate the significance of renal biopsy for patients who have been presumptively diagnosed...

Branch mispredictions is an important factor affecting the running time in practice. In this paper we consider tradeoffs between the number of branch mispredictions and the number of comparisons for sorting algorithms in the comparison model. We prove that a sorting algorithm using O(dn log n) comparisons performs Ω(n log d n) branch mispredictions. We show that Multiway MergeSort achieves this...