background: oral lichen planus (olp) is a chronic mucocutaneous lesion with unknown etiology. oral lichenoid lesions (oll) comprise a family of lesions with different etiologies. both lesions have similar clinical and histopathologic characteristics although their management is different. differential diagnosis between olp and oll has always been a major challenge. materials and methods: in thi...

Papillary glioneuronal tumor (PGNT) is a low-grade biphasic that composed of glial fibrillary acidic protein (GFAP)-positive cells and synaptophysin-positive neurons. We report case PGNT occurring in the right occipital lobe 48-year-old woman who presented with acute headache left homonymous hemianopsia, latter which was difficult to distinguish from malignant brain tumors because peritumoral e...

Various lines of evidence indicate the involvement of DNA strand breaks (DSB) in the regulation of physiological states of cells, especially in cell death. Currently, cell death is divided into two categories, apoptosis and necrosis. As lysosomal integrity is maintained in apoptosis, while disrupted in necrosis, it is possible to assume that necrotic chromatin is exposed to digestion by various...

Molecular probes for imaging of live cells are of great interest for studying biological and pathological processes. The anionic luminescent conjugated polythiophene (LCP) polythiophene acetic acid (PTAA), has previously been used for vital staining of cultured fibroblasts as well as transformed cells with results indicating differential staining due to cell phenotype. Herein, we investigated t...

BACKGROUND Chronic infection in cystic fibrosis (CF) and airway inflammation leads to progressive lung injury. Neutrophils are considered to be responsible for the onset and promotion of the inflammatory response within the CF lung. The relationship between infection and inflammation is complex but circulating inflammatory markers may not truly reflect the local inflammatory response in the lun...

We studied the expression and distribution of transforming growth factor-beta (TGF-beta) isoforms in the rat male accessory sex glands and the epididymis. Our data demonstrate the expression of both TGF-beta1 and -beta3 isoforms in ventral prostate (VP), seminal vesicle (SV), coagulating gland (CG), and epididymis (E) by Northern blot analysis. In addition, there was differential expression of ...

Dermatofibroma is a common benign fibrohistiocytic tumor with many clinicopathological variants. Myxoid dermatofibroma is one of these variants, which is characterized by marked stromal mucin deposition. This report presents a case of myxoid dermatofibroma on a great toe that had been slowly growing for two years. Histopathologically, the relatively well-circumscribed dermal tumor was separated...

Identify the red cells morphological changes (Peripheral blood smear) due to altered haematopoiesis resulting from HIV infection and the pathogenesis of red cells morphological changes in human immunodeficiency virus (HIV). Blood was collected in a sterile EDTA containing tube and processed following our established laboratory protocol and by universal precaution as per the guideline of Nationa...