Quantitative imaging approaches compute features within images' regions of interest. Segmentation is rarely completely automatic, requiring time-consuming editing by experts. We propose a new paradigm, called "digital biopsy," that allows for the collection of intensity- and texture-based features from these regions at least 1 order of magnitude faster than the current manual or semiautomated m...

Dear Editor, The selection of appropriate diagnostic techniques is an important step in the treatment of disease. An optimal diagnostic method can provide essential information, while minimizing cost and harm to patients. In dental radiography , attempts have been made to reduce patient exposure to radiation. Cone-beam computed tomography (CBCT) and digital radiography were developed to achieve...

The authors report interim clinical results from an ongoing NIH-sponsored trial to evaluate digital chest tomosynthesis for improving detectability of small lung nodules. Twenty-one patients undergoing computed tomography (CT) to follow up lung nodules were consented and enrolled to receive an additional digital PA chest radiograph and digital tomosynthesis exam. Tomosynthesis was performed wit...

In this study, the accuracy (precision and trueness) of digital impressions and the fitness of single crowns manufactured based on digital impressions were evaluated. #14-17 epoxy resin dentitions were made, while full-crown preparations of extracted natural teeth were embedded at #16. (1) To assess precision, deviations among repeated scan models made by intraoral scanner TRIOS and MHT and mod...

background and aims. cone-beam computed tomography (cbct) is an imaging system which has many advantages over computed tomography (ct). in ct scan, hounsfield unit (hu) is proportional to the degree of x-ray attenuation by the tissue. in cbct, the degree of x-ray attenuation is shown by gray scale (voxel value). the aim of the present study was to investigate the relationship between gray scale...

Today, considering global development of digital technology, experts not only strive to perfect methods of conventional ultrasound echographic imaging of tissue structure (US), but also intensively develop other methods, focusing especially on ultrasound transmission tomography (UTT) (analogous to X-ray computed tomography CT) and reflection tomography (URT) (based on synthetic aperture method ...

We present a digital spectral shaping technique to reduce the sidelobes (ringing) of the axial point-spread function in optical coherence tomography for non-Gaussian-shaped source spectra. The spectra of two superluminescent diodes were combined to generate a spectrum with significant modulation. Images of onion cells demonstrate the improved image quality in a turbid biological sample. A quant...

We present a 4 × 4 array of digital silicon photomultipliers (DSiPMs) capable of timestamping up to 48 photons per D-SiPM and we show the advantage of generating multiple timestamps in the context of positron emission tomography (PET). The D-SiPMs have a pitch of 800 μm and comprise 416 pixels each; the timing resolution achieved by the SiPMs is 179 ps FWHM, while each pixel has a fill factor o...

Endodontic treatments are routinely done with the help of radiographs. However, radiographs represent only a two-dimensional image of an object. Failure to identify aberrant anatomy can lead to endodontic failure. This case report presents the use of three-dimensional imaging with cone beam computed tomography (CBCT) as an adjunct to digital radiography in identification and management of mandi...

A nomalous origin of the right coronary artery (RCA) arising from the pulmonary trunk (PT) is rare, with an expected incidence of 0.002%. Numerous modalities are available to aid in establishing the diagnosis, including echocardiography, digital subtraction angiography, magnetic resonance angiography, and computed tomography coronary angiography (CTCA). We describe a case of anomalous origin of...