A new polymer vaginal pessary providing sustained constant release of prostaglandin E2 was administered to 66 patients before planned induction of labour. Effective ripening of the unfavourable cervix was achieved in each of 18 primigravidas, in eight of whom labour was initiated without further treatment. When the cervix was moderately favourable the need for orthodox induction of labour was o...

Colicin E2 was partially purified from Escherichia coli W3110. This preparation was remarkably stabilized by bovine serum albumin in a solution at neutral pH, as shown by dilution experiments and tests on heat stability of colicin. One killing unit of colicin E2 was estimated to correspond to one molecule of colicin E2, on the assumption of a molecular weight of 60,000.

In a prospective study of 52 consecutive women who required acceleration of labour intravenous prostaglandin E2 (PGE2) was used as the oxytocic agent. These mothers were matched for age, parity, height, gestational age, initial cervical dilatation, and station and position of the fetal head with 52 women whose labours were accelerated with oxytocin; both drugs were equally effective. Accelerati...

Polyubiquitylation is a complex but poorly understood biochemical reaction catalyzed by E3 ubiquitin ligases. In this issue of Cell, Deffenbaugh et al. provide experimental support for a model in which the dynamic release of the ubiquitin-charged E2 Cdc34 from its primary binding site within the rigid cradle-like SCF E3 complex allows for unexpected spatial flexibility to assemble a polyubiquit...

In this note the authors show that Kepler’s quartic curve with eccentricity e has λ-invariant e2 as an elliptic curve. Mathematics Subject Classification: 14H45, 37N05, 85-03

This paper studies an incompressible non-Newtonian fluid with delays in two-dimensional bounded domains. We first prove the existence and uniqueness of solutions. Then we establish the existence of pullback attractors {AC H (t)}t∈R (has L-regularity), {AC W (t)}t∈R (has H-regularity), and {AE2 H (t)}t∈R (has L-regularity), {A E2 W (t)}t∈R (has H-regularity) corresponding to two different proces...