All ceramic fixed partial dentures (FPD)s exhibit enhanced biocompatibility and esthetics as compared to metal-ceramic restorations. However, framework fractures are frequently reported especially when the connector dimensions are inadequate to withstand the high tensile stresses. The repair of the failed connector would be desirable rather than the complete removal and renewal since the latter...

Fhit protein is lost in most cancers, its restoration suppresses tumorigenicity, and virus-mediated FHIT gene therapy induces apoptosis and suppresses tumors in preclinical models. We have used protein cross-linking and proteomics methods to characterize a Fhit protein complex involved in triggering Fhit-mediated apoptosis. The complex includes Hsp60 and Hsp10 that mediate Fhit stability and ma...

The restoration of endodontic tooth is always a challenge for the clinician, not only due to excessive loss of tooth structure but also invasion of the biological width due to large decayed lesions. In this paper, the 7 most common clinical scenarios in molars with class II lesions ever deeper were examined. This includes both the type of restoration (direct or indirect) and the management of t...

This paper develops new algorithms belonging to the class of context modelling methods, with direct application to lossless coding of gray level images. The prediction stage and the context modelling stage are performed using nonlinear techniques rooted in the eld of order statistics nonlinear ltering, which proved competitive in image restoration applications. The new nonlinear predictors intr...

Ninety-six patients with permanent pacemakers have been followed up. The total number of faults and pacingbreakdowns has been large, but these are now becoming fewer with the introduction of better techniques. Furthermore, the majority of patients have been able to lead normal lives. Only one patient has died as a direct result of unit failure; the remainder survived a recurrence of Stokes-Adam...

Automatic speech recognition systems generally produce unpunctuated text which is difficult to read for humans and degrades the performance of many downstream machine processing tasks. This paper introduces a bidirectional recurrent neural network model with attention mechanism for punctuation restoration in unsegmented text. The model can utilize long contexts in both directions and direct att...

BACKGROUND Knowing which factors influence restoration longevity can help clinicians make sound treatment decisions. The authors analyzed data from The National Dental Practice-Based Research Network to identify predictors of early failures of amalgam and resin-based composite (RBC) restorations. METHODS In this prospective cohort study, the authors gathered information from clinicians and of...

Dental fractures of the permanent maxillary anterior teeth are relatively frequent accidents during childhood. The Efficient diagnosis and treatment of dental injury are important elements in clinical dentistry. This article describes a case of trauma in permanent right central maxillary incisors with tooth fragments embedded in the lower lip. Thorough clinical examination followed by soft tiss...

MicroRNAs (miRNAs) have been implicated in the orchestration of diverse cellular processes including differentiation, proliferation, and apoptosis and are believed to play pivotal roles as oncogenes and tumor suppressors. miR-122, a liver specific miRNA, is significantly down-regulated in most hepatocellular carcinomas (HCCs) but its role in tumorigenesis remains poorly understood. Here we iden...

A 58-year old male patient who had undergone post-infarction ventricular septal defect closure and venous coronary bypass grafting to the obtuse marginal artery 2 years previously, presented with congestive heart failure. Echocardiography, computed tomography and ventriculography revealed a giant inferoposterior left ventricular aneurysm (Fig. 1A–D, Supplementary Video 1). Surgical left ventric...