BACKGROUND Rotavirus is the leading cause of severe gastroenteritis in children worldwide. We evaluated the economic burden of rotavirus and the cost-effectiveness of vaccination from the health care perspective. METHODS Estimates were based on existing epidemiological data, cost estimates, vaccine coverage, and efficacy data, as well as hypothetical vaccine prices. Outcome measures included ...

OBJECTIVE To evaluate changes in the age-adjusted prevalence of disability in transitional China from 1987 to 2006. METHODS Data from nationally representative surveys conducted in 1987 and 2006 were used to calculate age-adjusted disability prevalence rates by applying appropriate sample weights and directly adjusting to the age distribution of the 1990 Chinese population. Trends were assess...

BACKGROUND The Medical Research Council of Canada (MRCC) is the major Canadian agency responsible for funding biomedical health research in this country. Disease-specific funding by the United States National Institutes of Health (NIH) has been studied and is not independent of burden-of-disease parameters. We tested the association between disease-specific MRCC funding, disease-specific NIH fu...

Abstract The purpose of this study was to quantify the sleep disturbances caused by climate change using disability-adjusted life years (DALY). revised quality index for daily (SQIDS2), a self-administered questionnaire quality, developed assess disturbances. This referenced and simplified Pittsburgh Sleep Quality Index (PSQI). conducted in Nagoya City August 2011 2012. measured SQIDS2 PSQI. A ...

Abstract The aim of this study was to assess temporal trends in disability benefits for breast cancer awarded women by Brazil’s National Social Security Institute. We conducted a time-series analysis benefit incidence rates between 2007 and 2018 using joinpoint regression data from the Unified Benefits Information System (SUIBE) open access social security system database. age-adjusted rate inc...

The use of the Quality Adjusted Life-Year (QALY) as a measure of the benefit obtained from health care expenditure has been attacked on the ground that it gives a lower value to preserving the lives of people with a permanent disability or illness than to preserving the lives of those who are healthy and not disabled. The reason for this is that the quality of life of those with illness or disa...