Discriminant analysis, including linear discriminant analysis (LDA) and quadratic (QDA), is a popular approach to classification problems. It well known that LDA suboptimal analyze heteroscedastic data, for which QDA would be an ideal tool. However, less helpful when the number of features in data set moderate or high, its variants often perform better due their robustness against dimensionalit...

Ion mobility spectrometry combined with multicapillary column separation (MCC-IMS) is a well-known technology for detecting volatile organic compounds (VOCs) in gaseous samples. Due to their large data size, processing of MCC-IMS spectra is still the main bottleneck of data analysis, and there is an increasing need for data analysis strategies in which the size of MCC-IMS data is reduced to ena...

BACKGROUND Chronic, low-grade inflammation and declining physical function are hallmarks of the aging process. However, previous attempts to correlate individual inflammatory biomarkers with physical performance in older people have produced mixed results. Given the complexity of the inflammatory response, the simultaneous analysis of an array of inflammatory mediators may provide more insights...

Multiple Myeloma (MM) is a severely debilitating neoplastic disease of B cell origin, with the primary source of morbidity and mortality associated with unrestrained bone destruction. Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) was used to screen for potential biomarkers indicative of skeletal involvement in patients with MM. Serum samples from 4...

The texture of cooked chicken breast is usually determined on intact pieces or strips that are representative of the muscle. Researchers emphasize the importance of uniformity of sample size and orientation of fibers to the shearing blades to ensure consistent data from instruments such as shear devices. For sensory evaluations, sample pieces of chicken breasts presented to panelists are often ...

BACKGROUND AND AIMS Proton nuclear magnetic resonance spectroscopy coupled multivariate analysis (1H NMR-PCA/PLS-DA) is an important tool for the discrimination of wine products. Although 1H NMR has been shown to discriminate wines of different cultivars, a grape genetic component of the discrimination has been inferred only from discrimination of cultivars of undefined genetic homology and in ...

Linear discriminant analysis for multiple groups is typically carried out using Fisher’s method. This method relies on the sample averages and covariance matrices computed from the different groups constituting the training sample. Since sample averages and covariance matrices are not robust, it is proposed to use robust estimators of location and covariance instead, yielding a robust version o...

This study provides a financial analysis of those firms that during the recent period of economic recession and financial market turmoil beginning in December 2007 and continuing to June 2009 either maintained or increased the total compensation packages for their chief executive officers and other executives in their firms. Specifically, this analysis will test for significant differences in t...

Gentiana rigescens is a precious herbal medicine in China because of its liver-protective and choleretic effects. A method for the qualitative identification and quantitative evaluation of G. rigescens from Yunnan Province, China, has been developed employing Fourier transform infrared (FT-IR) spectroscopy and high performance liquid chromatography (HPLC) with the aid of chemometrics such as pa...