BACKGROUND Phenotypic traits of familial IBD relative to sporadic cases are controversial, probably related to limited statistical power of published evidence. AIM To know if there are phenotype differences between familial and sporadic IBD, evaluating the prospective Spanish registry (ENEIDA) with 11,983 cases. METHODS 5783 patients (48.3%) had ulcerative colitis (UC) and 6200 (51.7%) Croh...

The mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders characterized by a wide variation in symptoms and progression rates. Each of the MPS types is caused by a deficiency in one of the enzymes involved in the catabolic pathway of glycosaminoglycans. MPS are usually suspected on the basis of the concomitant presence of several typical features of the disease, such as short s...

Even though the pandemic caused by Influenza A(H1N1)pdm09 (pH1N1) infection has been extensively investigated, there are few studies that have examined the impact of viral coinfection on disease severity, and they have yielded conflicting results. In this issue of the Jornal de Pediatria, Scotta et al.1 report on a retrospective study of 120 Brazilian children hospitalized with pH1N1 infection,...

Abnormal iron distribution in the isocortex is increasingly recognized as an in vivo marker for Alzheimer's disease (AD). However, the contribution of iron accumulation to the AD pathology is still poorly understood. In this study, we investigated: 1) frontal cortical iron distribution in AD and normal aging and 2) the relation between iron distribution and degree of AD pathology. We used forma...

Accurate assessment of idiopathic pulmonary fibrosis (IPF) disease severity is integral to the care provided to patients with IPF. However, to date, there are no generally accepted or validated staging systems. There is an abundance of data on using information acquired from physiological, radiological and pathological parameters, in isolation or in combination, to assess disease severity in IP...

2007;132;164-169; Prepublished online May 15, 2007; Chest Koulouris and Stelios Loukides Eleni Ischaki, Georgios Papatheodorou, Eleni Gaki, Ioli Papa, Nikolaos * COPD Body Mass and Fat-Free Mass Indices in http://www.chestjournal.org/content/132/1/164.full.html and services can be found online on the World Wide Web at: The online version of this article, along with updated information ) ISSN:00...

among 160 samples collected from rice paddy of the guilan province including rice plant, seed, rhizospher, paddy's soil, paddy's water and sclerotium of the causal agent of rice sheath blight (rhizoctonia solani), 610 bacterial strains were isolated. 71 bacterial strains (11.64%) had the ability of inhibition mycelial growth fungus in dual culture test on pda medium. according to two characteri...

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Severe NonProliferative Diabetic Retinopathy Any of the following: € Extensive (>20) intraretinal hemorrhages in each of 4 quadrants € Definite venous beading in 2+ quadrants € Prominent IRMA in 1+ quadrant € And no signs of proliferative retinopathy 53A-E: severe to very severe NPDR, 4:2:1 rule One year risk for early PDR: 50.2% (severe NPDR) One year High Risk PDR: 14.6% (severe NPDR) – 45.0%...

Background and Objective: The COVID-19 pandemic is a phenomenon that has infected and killed many people worldwide. Underlying diseases such as diabetes mellitus, heart failure, and chronic kidney disease (CKD) can affect the severity of COVID-19 and aggravate patients' condition. This study aimed to predict the severity of the COVID-19 disease in CKD patients by combining feature selection and...