To study the usefulness of glycerin fatty acid ester Poem TR-FB (TR-FB) and Poem TR-HB (TR-HB) as lubricants, pressure transmission ratio, ejection force, disintegration time, and tensile strength were measured at different concentrations and mixing times for granules and tablets. When each lubricant was mixed at 0.1-3.0%, the increase in the pressure transmission ratio that was equal to or gre...

The main objectives of this study were (a) to evaluate the in vitro performance of the rapid disintegration tablets as a way to improve the solid dispersions and (b) to study the in vivo pharmacokinetics of the albendazole modified formulation in dogs. Rapid disintegration of tablets seems to be a key factor for efficiency of solid dispersions with regard to improvement of the albendazole bioav...

An explicit evaluation of the spin asymmetry of the deuteron and the associated GDH sum rule is presented which includes disintegration, single and double pion and eta production. For the GDH integral a large cancellation is found between the disintegration channel and the meson production channels. Furthermore, first results for the contribution of the disintegration channel to the generalized...

The notions of disintegration and Bayesian inversion are fundamental in conditional probability theory. They produce channels, as conditional probabilities, from a joint state, or from an already given channel (in opposite direction). These notions exist in the literature, in concrete situations, but are presented here in abstract graphical formulations. The resulting abstract descriptions are ...

a research program was conducted on different clay-bearing rocks selected from the ilam, sarpol-e zahab and tajarak regions (iran) to predict their slaking characteristics. the new durability apparatus (nested mesh drums) separates disintegrated particles varying from > 25.4 to < 2 mm as the drums were rotated. on the basis of the particle size distribution, the disintegration ratio (dr) was us...

The objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. Captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...