BACKGROUND Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine. The analysis of these lipid fractions is demanding and time consuming and total phospholipid n-3 fatty acid levels might be affected by changes of sphingomyelin con...

BACKGROUND Omega-3 fatty acids in free fatty acid form have enhanced bioavailability, and plasma levels are less influenced by food than for ethyl ester forms. OBJECTIVE The aim was to evaluate the safety and lipid-altering efficacy in subjects with severe hypertriglyceridemia of an investigational pharmaceutical omega-3 free fatty acid (OM3-FFA) containing eicosapentaenoic acid and docosahex...

The fruity odours of wine are largely derived from the synthesis of esters and higher alcohols during yeast fermentation. The ATF1- and ATF2-encoded alcohol acetyltransferases of S. cerevisiae are responsible for the synthesis of ethyl acetate and isoamyl acetate esters, while the EHT1-encoded ethanol hexanoyl transferase is responsible for synthesizing ethyl caproate. However, esters such as t...

Omega-3 fatty acid products are available as prescription formulations (icosapent ethyl, omega-3-acid ethyl esters, omega-3-acid ethyl esters A, omega-3-carboxylic acids) and dietary supplements (predominantly fish oils). Most dietary supplements and all but one prescription formulation contain mixtures of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Produ...

This paper presents the volumetric velocity measurement method of small seeding tracer with diameter 5µm ∼ 100µm for volumes ≥ 500cm3. The size is between helium-filled soap bubbles (HFSB) and di-ethyl-hexyl-sebacic acid ester(DEHS) droplets. targeted volume dimension equivalent to HFSB, which will give a higher resolution turbulence study. relations particle size, imaging light intensity are f...

BACKGROUND AND OBJECTIVE Icosapent ethyl is a high-purity prescription form of eicosapentaenoic acid ethyl ester approved as an adjunct to diet to reduce triglyceride levels in adult patients with triglyceride levels ≥500 mg/dL (≥5.65 mmol/L). The objective of this open-label, drug-drug interaction study was to examine the effects of icosapent ethyl on the steady-state pharmacokinetics of atorv...

The antioxidant activity of Annona squamosa (A. squamosa) leaf was carried out using methanol extract and fractionated namely n-hexane, ethyl acetate residue. performed the 1-diphenyl-2-Pycrilhydrazil (DPPH) method. test residue yielded IC50 6.87, 169.99, 31.55 44.75 ppm. fraction with ppm by column chromatography silica gel G60 as stationary phase n-hexane: mobile phase. results obtained 181 f...

The leaves of parthenium (Parthenium hysterophorus L.) were extracted in ethanol and toxicity the extract was examined on khapra beetle (Trogoderma granarium Everts) larvae. Four concentrations (2, 4, 6 8 µL mL-1 acetone) applied directly larvae Petri dishes. Toxicity recorded after 12, 24 36 h. All had considerable effect mortality At highest concentration (8 mL-1), observed 57%, 72% 78% h, re...

AIM This study was designed to investigate the bioactive compounds in Costus afer Ker Gawl, an indigenous African medicinal plant whose leaf and stem extracts are used in the treatment of chronic inflammatory diseases, especially rheumatism and arthritis. MATERIALS AND METHODS The bioactive compounds present in the n-butanol fractions of C. afer leaf and stem were identified using qualitative...

Abbreviations: ACL5, ACAULIS5; ATHB8, ARABIDOPSIS THALIANA HOMEOBOX8; bHLH, basic helix-loop-helix; 2,4-D IOE, isooctyl ester of 2,4-dichlorophenoxyacetic acid; EMS, ethyl methanesulfonate; GUS, β-glucuronidase; LHW, LONESOME HIGHWAY; mORF, main open-reading frame; MP, MONOPTEROS; PAO, POLYAMINE OXIDASE; SAC, SUPPRESSOR-OF-ACL5; SACL, SAC-LIKE; SAMDC, S-adenosylmethionine decarboxylase; TMO5, T...