The postulate that twice the milligram/kilogram dose of dl-methylphenidate (dl-MPH) would result in equal exposure to d-MPH compared with half that milligram/kilogram dose of the chiral switch product dexmethylphenidate (d-MPH) was tested. Using a randomized, crossover study design, 12 men and 12 women received either immediate-release (IR) dl-MPH (0.3 mg/kg) or IR d-MPH (0.15 mg/kg). Relative ...

Objective: The aim of this study was two fold. To determine the diagnostic reference level (D.R.L.) dose of radiation during dynamic hip screw (D.H.S.) fixation and, to audit the orthopaedic department against this standard. Methods and Materials: A retrospective analysis of 112 consecutive patients between 31st December 2002 and the 6th July 2003, at Darenth Valley Hospital, Dartford, under go...

BACKGROUND Growing evidence suggests that the left radial approach (LRA) is related to decreased coronary procedure duration and fewer cerebrovascular complications as compared to the right radial approach (RRA) in elective percutaneous coronary intervention (PCI). However, the feasibility of LRA in primary PCI has yet to be studied further. Therefore, the aim of this study was to investigate t...

OBJECTIVES This study sought to perform a randomized noninferiority trial of radiation exposure during cardiac catheterization comparing femoral access (FA) with left radial access (LRA) and right radial access (RRA). BACKGROUND Increased radiation exposure with radial approach compared with femoral approach remains a controversial issue. METHODS This study randomized 1,493 patients undergo...

We have completed a phase I trial in women of the proposed chemopreventive natural product indole-3-carbinol (I3C). Women received oral doses of 400, 600, 800, 1,000, and 1,200 mg I3C. Serial plasma samples were analyzed by high-performance liquid chromatography-mass spectrometry for I3C and several of its condensation products. I3C itself was not detectable in plasma. The only detectable I3C-d...

Energy imparted is a measure of the total ionizing energy deposited in the patient during a radiologic examination and may be used to quantify the patient dose in diagnostic radiology. Values of the energy imparted per unit exposure-area product, omega (z), absorbed by a semi-infinite water phantom with a thickness z, were computed for x-ray spectra with peak x-ray tube voltages ranging from 50...

background: natural background radiation of a particular region is one of the distinctive factors defining the status of environment. eloor island is an industrial area in ernakulum district of the state of kerala, india. the indoor and outdoor gamma level measurements have been carried out for the region for evaluating the annual effective dose to the population residing in this area. material...

Distal transradial approach (dTRA) is safe and effective for coronary angiography PCI. However, its impact on radiation exposure in the catheterization laboratory has not been characterized. We performed a systematic review meta-analysis of scientific literature by searching PubMed, Embase, Cochrane Library databases with relevant terms until October 13, 2022. Randomized controlled trials (RCTs...

methods in this article we checked the derived data from 20 relevant studies published during the last 20 years in international scientific literature at other country except iran and 10 studies from iran. the variables dose-area product (dap), fluoroscopy time, number of sequences and frames per sequence were collected for each ca, ptca, rfa and diagnostic electrophysiology and then the obtain...

Coronary angiography (CA) procedure uses various angiographic projections to elicit detailed information of the coronary arteries with some steep projections involving high radiation dose to patients. This study intends to evaluate radiation doses and estimated risk from angiographic projections during CA procedure performed using novel flat detector (FD) system with improved image processing a...