نتایج جستجو برای: dose dependency
تعداد نتایج: 349552 فیلتر نتایج به سال:
This randomized, prospective study was conducted in 76 subjects to assess whether low-dose (0.5-2 mg/day) glimepiride, in combination therapy with sitagliptin, improves glycemic control in a dose-dependent manner in Japanese patients with type 2 diabetes. Eligible subjects had been treated with glimepiride at doses of 3-6 mg/day for at least 3 months and had a HbA1c level of ≥6.9%. Subjects wer...
Dependency parser is one of the most important fundamental tools in the natural language processing, which extracts structure of sentences and determines the relations between words based on the dependency grammar. The dependency parser is proper for free order languages, such as Persian. In this paper, data-driven dependency parser has been developed with the help of phrase-structure parser fo...
BACKGROUND Despite intriguing observational cross-sectional data there are no longitudinal studies of opiate related arterial disease. As opiates act via P16INK4A/CDKN2A, and vascular ageing has been thought to be a surrogate for organismal ageing, the subject has far-reaching implications. METHODS Pulse Wave Analysis (PWA) by radial arterial tonometry (SphygmoCor) was performed on control an...
BACKGROUND Intra-articular (IA) corticosteroid therapy has been used for the treatment of inflammation and pain in the knee since the 1950s. PURPOSE To review the current literature on the effects of IA corticosteroids on articular cartilage. STUDY DESIGN Systematic review. METHODS A MEDLINE and SCOPUS database search was performed, and studies were selected for basic science and clinical...
PURPOSE The purpose is to determine the maximum-tolerated dose, assess the toxicities, characterize the pharmacokinetic behavior, and seek preliminary evidence of biological activity of cantuzumab mertansine when administered as a weekly i.v. infusion without interruption. EXPERIMENTAL DESIGN Patients with incurable solid tumors that expressed the target antigen for cantuzumab mertansine, Can...
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