Fragmented 18-day chick embryo gonads were explanted on synthetic media in the presence of hCG added to 24 h cultures at the beginning (0 h) and to 48 h cultures, only after 24 h or at 0 and 24 h. The production of seven steroids was assayed by RIA and compared to that of control cultures containing no hCG. The levels were expressed as in vitro production per gonad (after deduction of the non-e...

Chorioamnionitis has been shown to be one of the most important factors in inducing preterm delivery. The present study was undertaken to examine the effects of chorioamnionitis on placental endocrine functions. Preterm placentas with histologic chorioamnionitis produced smaller amounts of human chorionic gonadotropin (hCG) and human placental lactogen (hPL) than those without chorioamnionitis ...

Discordance has been reported in human chorionic gonadotropin (hCG) concentrations measured by different immunoassay kits. We examined the results for 40 serum samples assayed with 10 different hCG immunoassay kits. Results varied considerably. Individual sample results varied by as much as 58-fold. Average results for different kits varied by as much as 1.4-fold for pregnancy (20 samples) and ...

Even in the advanced era of today, maternal morbidity and mortality are quite high; however, most pregnancy-related complications can be successfully prevented by early diagnosis timely management. The primary care setting is utmost importance this regard, as it first line contact between patients physicians, regular antenatal services provided settings. Ectopic pregnancy one prevalent disorder...

BACKGROUND Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone that exists in multiple forms. Immunoassays commonly used in clinical laboratories measure intact hCG, total beta hCG (intact hCG + hCG free beta-subunit), and/or hCG free beta-subunit. Measurement of serum concentrations of hCG is useful for confirmation and monitoring of pregnancy, diagnosis of trophoblastic...

Non-seminomatous germ cell tumors producing human chorionic gonadotropin (HCG) were first described in 1964. HCG is capable of inducing hyperthyroidism by stimulating the TSH receptor, due to its identical alpha subunit. We report a case HCG-mediated setting choriocarcinoma. A 28-year-old man presented with 3-week history unintentional weight loss, cough, hemoptysis, palpitations, shortness bre...